Miller-Johnson S, Lochman J E, Coie J D, Terry R, Hyman C
Department of Psychology, Duke University, Durham, NC 27708, USA.
J Abnorm Child Psychol. 1998 Jun;26(3):221-32. doi: 10.1023/a:1022676302865.
The comorbidity of conduct and depressive problems and substance use outcomes were examined in a community-based sample of 340 African American males and females. Alcohol, tobacco, and marijuana use were examined at Grades 6, 8, and 10 based on the following group membership at sixth grade: (a) comorbid conduct and depressive problems; (b) conduct problems only; (c) depressive problems only; (d) neither conduct nor depressive problems. Overall, the two conduct problem groups displayed the highest levels of substance use, although at some time points, comorbid youth displayed significant higher substance use levels. Subjects with depressive problems only displayed levels of substance use that were equivalent to subjects in the nonproblem group. Results highlight the importance of controlling for comorbid symptoms, possible interactive effects between conduct and depressive problems, and implications for treatment and prevention of substance use.
在一个由340名非裔美国男性和女性组成的社区样本中，对品行问题与抑郁问题的共病情况以及物质使用结果进行了研究。根据六年级时的以下分组情况，在六年级、八年级和十年级对酒精、烟草和大麻的使用情况进行了调查：（a）品行问题与抑郁问题共病；（b）仅存在品行问题；（c）仅存在抑郁问题；（d）既无品行问题也无抑郁问题。总体而言，两个品行问题组的物质使用水平最高，不过在某些时间点，共病青少年的物质使用水平显著更高。仅存在抑郁问题的受试者的物质使用水平与无问题组的受试者相当。研究结果凸显了控制共病症状的重要性、品行问题与抑郁问题之间可能存在的交互作用，以及对物质使用治疗和预防的启示。
