黑质卒中与帕金森综合征作为系统性红斑狼疮的首发表现

Stroke of the substance nigra and parkinsonism as first manifestation of systemic lupus erythematosus.

作者信息

Orta Daniel San-Juan, Ulises Rodríguez-Ortiz

机构信息

Department of Neurology, National Institute of Neurology and Neurosurgery, "Manuel Velasco Suárez", Mexico City, Av. Insurgentes, 3877 Col. La Fama, 14269 Tlalpan, México, D.F., Mexico.

出版信息

Parkinsonism Relat Disord. 2008;14(4):367-9. doi: 10.1016/j.parkreldis.2007.08.001. Epub 2008 May 2.

DOI:10.1016/j.parkreldis.2007.08.001

PMID:18455950

Abstract

The authors report one case of parkinsonism associated with systemic lupus erythematosus (SLE): a 45-year-old woman, who presented with a strategic infarct of the right substance nigra secondary to vasculitis, and contralateral symptoms. Other causes of parkinsonism were excluded. She had a partial response to therapy with levodopa. Parkinsonism as the first manifestation of lupus is extremely rare. This is the first reported case with strategic infarction in the substance nigra secondary to vasculitis in a patient with SLE.

摘要

作者报告了一例与系统性红斑狼疮（SLE）相关的帕金森综合征病例：一名45岁女性，因血管炎继发右侧黑质梗死，并出现对侧症状。排除了帕金森综合征的其他病因。她对左旋多巴治疗有部分反应。帕金森综合征作为狼疮的首发表现极为罕见。这是首例报告的SLE患者因血管炎继发黑质梗死的病例。