Nordenvall B, Backman L, Larsson L, Tiselius H G
Acta Chir Scand. 1983;149(1):93-8.
The urinary excretion of oxalate, calcium, magnesium and citrate as well as the inhibition of calcium oxalate crystal growth in diluted urine was studied in seven patients with hyperoxaluria following jejunoileal bypass. The study was performed on an outpatient basis before and during daily administration of 38 or 113 mmol calcium, 28 mmol of aluminum, 20 mmol of magnesium or 16 g of cholestyramine. Each substance was administered for seven days with a free interval of at least seven days. The mean urinary oxalate excretion was not reduced with any of these regimens. Administration of 38 mmol of calcium per day resulted in increased oxalate and magnesium excretion. Increased excretion of both calcium and citrate was observed during administration of 113 mmol of calcium per day. Calcium and magnesium excretion was increased with aluminium. An increased magnesium excretion was also observed during administration of magnesium, resulting in a decreased calcium/ magnesium ratio. Cholestyramine resulted in increased oxalate and decreased citrate excretion.
对7例空肠回肠旁路术后高草酸尿症患者的草酸盐、钙、镁和柠檬酸盐的尿排泄以及稀释尿液中草酸钙晶体生长的抑制情况进行了研究。该研究在门诊进行，于每日给予38或113 mmol钙、28 mmol铝、20 mmol镁或16 g消胆胺之前及期间开展。每种物质给药7天，至少间隔7天。这些方案均未降低平均尿草酸盐排泄量。每日给予38 mmol钙导致草酸盐和镁排泄增加。每日给予113 mmol钙期间，钙和柠檬酸盐排泄均增加。铝使钙和镁排泄增加。给予镁期间也观察到镁排泄增加，导致钙/镁比值降低。消胆胺导致草酸盐排泄增加和柠檬酸盐排泄减少。
