Vanherweghem J L, Quenon M, Dhaene M, Goldman M, Philippart Y, Stolear J C, Thayse C, Waterlot Y
Nephrologie. 1984;5(4):184-8.
The effects on urinary excretion of a 1500 ml daily load of three drinking waters with different ionic contents were studied in six normal subjects. Diuresis was similarly increased by the three waters of an amount equal to the load. Urine output of urea, creatinin, uric acid, phosphate, potassium, magnesium was not significantly modified by the three waters as compared to a control period. Natriuresis was significantly increased following the intake of the water which contained sodium as well as calciuria with the water containing calcium. Urine output of oxalate was increased by the three waters in correlation with the free water content of the load. This effect is probably due to a reduction in passive tubular reabsorption of oxalate since a similar effect was observed with an equivalent water load given by intravenous route. Nevertheless, due to the dilution of urine, the index of urine saturation for calcium oxalate was diminished by the three waters.
在六名正常受试者中研究了每天摄入1500毫升三种不同离子含量的饮用水对尿排泄的影响。三种水引起的利尿作用类似，增加量与摄入量相等。与对照期相比，三种水对尿素、肌酐、尿酸、磷酸盐、钾、镁的尿量排泄没有显著改变。摄入含钠的水后，尿钠排泄显著增加，摄入含钙的水后，尿钙排泄增加。三种水使草酸盐尿量排泄增加，与摄入水中的自由水含量相关。这种作用可能是由于肾小管对草酸盐的被动重吸收减少，因为静脉给予等量水负荷时也观察到类似作用。然而，由于尿液稀释，三种水使草酸钙的尿液饱和度指数降低。
