Kolb Stefanie, Radon Katja, Valois Marie-France, Héguy Léa, Goldberg Mark S
Unit for Occupational and Environmental Epidemiology & NetTeaching, Institute for Occupational and Environmental Medicine, Munich, Germany.
Arch Environ Occup Health. 2007 Winter;62(4):169-76. doi: 10.3200/AEOH.62.4.169-176.
The authors' purpose in this study was to determine whether changes in weather conditions were associated with daily mortality among people aged 65 years and older diagnosed as having congestive heart failure in Montreal, Canada, and who died in the urban area between 1984 and 1993. The authors used a time-stratified case-crossover design and adjusted the models for nitrogen dioxide and ozone. They found a strong nonlinear association with maximum temperature in the warmer months of the year, with a threshold at about 25 degrees C. The authors observed no associations after lag 3 days. In the cold period, they found that risks increased linearly with increasingly colder temperatures, but only after lag 2 days. The authors found no associations with relative humidity. For change in barometric pressure from the previous day, they found no associations in the cold period, but an increase in pressure from the previous day increased risk for lags 0 or 1 days. The authors found some differences between men and women.
作者开展此项研究的目的是确定天气状况的变化是否与加拿大蒙特利尔市65岁及以上被诊断为充血性心力衰竭且于1984年至1993年间在市区死亡的人群的每日死亡率相关。作者采用了时间分层病例交叉设计，并对二氧化氮和臭氧模型进行了调整。他们发现，在一年中较温暖的月份，与最高温度存在强烈的非线性关联，阈值约为25摄氏度。作者观察到滞后3天后无关联。在寒冷时期，他们发现风险随温度降低呈线性增加，但仅在滞后2天后出现。作者未发现与相对湿度有关联。对于前一日气压的变化，他们发现在寒冷时期无关联，但前一日气压升高会增加滞后0或1天的风险。作者发现男性和女性之间存在一些差异。
