Garey Donna M, Ward Raymond, Rich Wade, Heldt Gregory, Leone Tina, Finer Neil N
University of California, Division of Neonatology, 402 Dickinson St, MPF 1-140 #8774, San Diego, CA 92103-8774, USA.
Pediatrics. 2008 Jun;121(6):e1524-7. doi: 10.1542/peds.2007-2708. Epub 2008 May 5.
Colorimetric carbon dioxide detectors are used for confirmation of endotracheal intubation. The colorimetric carbon dioxide detectors that are used for neonates are labeled for use with infants and small children >1 and <15 kg. The objective of this study was to determine the minimal tidal volume that causes a breath-to-breath color change on 2 colorimetric carbon dioxide detectors.
Using an artificial-lung model, we determined the tidal volume threshold of 2 colorimetric carbon dioxide detectors (Pedi-Cap [Nellcor, Pleasanton, CA] or Mini StatCO(2) [Mercury Medical, Clearwater, FL]) during ventilation with a T-piece resuscitator or neonatal ventilator. Digital video recordings of the colorimetric carbon dioxide detectors were made during 20 seconds of ventilation at each tidal volume. Seven clinicians who were blinded to the tidal volume reviewed the videos in random order and graded the color change to determine adequacy for clinical application.
The Mini StatCO(2) tidal volume threshold was 0.83 mL, and the Pedi-Cap tidal volume threshold was 1.08 mL.
The lung model revealed that the tidal volume threshold for the tested colorimetric carbon dioxide detectors is less than the expected tidal volume of a 400-g infant and suggests that these devices are appropriate for use with any neonate to confirm intubation.
比色法二氧化碳探测器用于确认气管插管。用于新生儿的比色法二氧化碳探测器标明适用于体重>1千克且<15千克的婴儿和小儿。本研究的目的是确定在两种比色法二氧化碳探测器上引起逐次呼吸颜色变化的最小潮气量。
使用人工肺模型，我们在使用T形管复苏器或新生儿呼吸机通气期间，确定了两种比色法二氧化碳探测器（小儿帽式[Nellcor公司，普莱森顿，加利福尼亚州]或Mini StatCO₂[水星医疗公司，克利尔沃特，佛罗里达州]）的潮气量阈值。在每个潮气量通气20秒期间，对比色法二氧化碳探测器进行数字视频记录。七名对潮气量不知情的临床医生以随机顺序查看视频，并对颜色变化进行分级，以确定其临床应用的适用性。
Mini StatCO₂的潮气量阈值为0.83毫升，小儿帽式的潮气量阈值为1.08毫升。
肺模型显示，测试的比色法二氧化碳探测器的潮气量阈值低于400克婴儿的预期潮气量，表明这些设备适用于任何新生儿以确认插管。
