Finer Neil N, Rich Wade, Wang Casey, Leone Tina
UCSD Medical Center, 402 W Dickenson St 8774, San Diego, CA 92103-8774, USA.
Pediatrics. 2009 Mar;123(3):865-9. doi: 10.1542/peds.2008-0560.
The delivery of adequate but not excessive ventilation remains one of the most common problems encountered during neonatal resuscitation, especially in the very low birth weight infant. Our observations suggest that airway obstruction is a common occurrence after delivery of such infants, and we use colorimetric carbon dioxide detectors during bag-and-mask resuscitation to assist in determining whether the airway was patent. We reviewed our experience to determine the frequency of the occurrence of recognizable airway obstruction during resuscitation of very low birth weight infants.
The previous prospective trial randomly assigned preterm infants <32 weeks' gestation to resuscitation with either room air or 100% oxygen using pulse oximetry. Colorimetric carbon dioxide detectors were used to assist with bag-and-mask ventilation and to confirm intubation. From the video recordings, the number of positive pressure breaths without a color change in the detector until the breaths were associated with an unequivocal color change was counted as obstructed breaths. From the analog tracings, the number of breaths that had a peak pressure plateau of >/=0.2 second and were not associated with a color change was recorded as the number of obstructed breaths.
None of the studied infants required cardiopulmonary resuscitation or received epinephrine, and all were judged to have an effective circulation during resuscitation. Six of the 24 infants enrolled in the trial received only continuous positive airway pressure. The remaining 18 infants received a median of 14 obstructed breaths (range: 4-37 breaths) delivered over a mean and median interval of 56.7 and 45.0 seconds, respectively (range: 10.0-220.0 seconds). A subgroup of 11 infants was analyzed using airway-pressure data. The target peak inspiratory pressure was 30 cm H(2)O. Ten of these 11 infants had obstructed breaths as defined by no change in the PediCap despite reaching the target pressure for >/=0.2 second.
Airway obstruction occurs in the majority of the very low birth weight infants who receive ventilation with a face mask during resuscitation and the use of a colorimetric detector can facilitate its recognition and management.
提供适度而非过度的通气仍然是新生儿复苏过程中最常见的问题之一,尤其是在极低出生体重儿中。我们的观察表明,此类婴儿出生后气道梗阻很常见,并且我们在面罩复苏期间使用比色二氧化碳探测器来协助确定气道是否通畅。我们回顾了我们的经验,以确定极低出生体重儿复苏期间可识别气道梗阻的发生频率。
先前的前瞻性试验将孕周<32周的早产儿随机分为使用脉搏血氧饱和度仪以空气或100%氧气进行复苏。比色二氧化碳探测器用于协助面罩通气并确认插管。从视频记录中,将探测器未发生颜色变化的正压通气次数,直到通气与明确的颜色变化相关联时,计为梗阻性通气次数。从模拟描记图中,将峰值压力平台期>/=0.2秒且与颜色变化无关的通气次数记录为梗阻性通气次数。
所研究的婴儿均无需心肺复苏或接受肾上腺素治疗,并且所有婴儿在复苏期间均被判定有有效的循环。该试验纳入的24名婴儿中有6名仅接受持续气道正压通气。其余18名婴儿接受的梗阻性通气次数中位数为14次(范围:4 - 37次),平均和中位数间隔时间分别为56.7秒和45.0秒(范围:10.0 - 220.0秒)。使用气道压力数据对11名婴儿的亚组进行了分析。目标吸气峰压为30 cm H(2)O。这11名婴儿中有10名尽管达到目标压力>/=0.2秒,但根据PediCap无变化定义为存在梗阻性通气。
大多数在复苏期间接受面罩通气的极低出生体重儿会发生气道梗阻,并且使用比色探测器有助于识别和处理气道梗阻。