Manafi S A, Yazdani B, Rahimiopour M R, Sadrnezhaad S K, Amin M H, Razavi M
Ceramic Department, Materials and Energy Research Center, PO Box 14155-4777, Tehran, Iran.
Biomed Mater. 2008 Jun;3(2):025002. doi: 10.1088/1748-6041/3/2/025002. Epub 2008 Mar 25.
In this study, hydroxyapatite (denoted as HAp) nanostructure with uniform morphologies, controllable size, nano-dispersion and narrow size distribution in diameter has been synthesized successfully by low-temperature hydrothermal process, and the as-synthesized powders were characterized by XRD, scanning electron microscopy, high-resolution transmission microscopy, FT-IR, Zetasizer and inductively coupled plasma. In the present work, a novel sonochemical technique using CaHPO(4)2H(2)O/NaOH/distilled water with cetyltrimethylammonium bromide ((CH(3)(CH(2))(15)N(+)(CH(3))(3)Br(-)) designated as CTAB) under a hydrothermal condition to synthesize HAp nanostructure was described. Furthermore, the usage of a high basic condition and a water environment are the two crucial keys in ensuring the formation of HAp in the hydrothermal/sonochemical processes. However, the crystallite size and crystallinity degree of the HAp increased with increasing annealing temperature. Indeed, the present work will introduce a new method in synthesizing HAs for scientific and medical engineering.
在本研究中，通过低温水热法成功合成了具有均匀形貌、尺寸可控、纳米分散且直径尺寸分布窄的羟基磷灰石（记为HAp）纳米结构，并采用X射线衍射、扫描电子显微镜、高分辨率透射显微镜、傅里叶变换红外光谱、Zeta电位分析仪和电感耦合等离子体对合成的粉末进行了表征。在本工作中，描述了一种新颖的声化学技术，即在水热条件下使用CaHPO₄·2H₂O/NaOH/蒸馏水与十六烷基三甲基溴化铵（(CH₃(CH₂)₁₅N⁺(CH₃)₃Br⁻)，记为CTAB）来合成HAp纳米结构。此外，高碱性条件和水环境的使用是在水热/声化学过程中确保HAp形成的两个关键因素。然而，HAp的微晶尺寸和结晶度随退火温度的升高而增加。实际上，本工作将为科学和医学工程领域引入一种合成羟基磷灰石的新方法。
