Kamitakahara Masanobu, Ohtsuki Chikara, Miyazaki Toshiki
Graduate School of Environmental Studies, Tohoku University, 6-6-20, Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan.
Biomed Mater. 2007 Dec;2(4):R17-23. doi: 10.1088/1748-6041/2/4/R01. Epub 2007 Nov 2.
Materials with bioactivity, i.e. bone-bonding ability, form a bone-like apatite layer on their surfaces in the body and bond to living bone through this bone-like apatite layer. Bone-like apatite is carbonated hydroxyapatite with small crystallites and low crystallinity. The coating of the bone-like apatite layer on the substrates is expected to be a useful technique to induce bioactivity on the substrates. The bone-like apatite layer can be formed on the surface of substrates in a solution mimicking body fluid when some functional groups are introduced to the substrates. This process is called a biomimetic process. Coating of bone-like apatite layers through this biomimetic process has received much attention in the fabrication of novel composites with bioactivity. An overview of the coating of bone-like apatite is described.
具有生物活性（即骨结合能力）的材料在体内其表面会形成一层类骨磷灰石层，并通过这层类骨磷灰石层与活骨结合。类骨磷灰石是具有小晶粒和低结晶度的碳酸羟基磷灰石。在基底上涂覆类骨磷灰石层有望成为一种在基底上诱导生物活性的有用技术。当向基底引入一些官能团时，类骨磷灰石层可以在模拟体液的溶液中在基底表面形成。这个过程称为仿生过程。通过这种仿生过程涂覆类骨磷灰石层在具有生物活性的新型复合材料的制造中受到了广泛关注。本文描述了类骨磷灰石涂层的概述。
