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使用碘化油经动脉化疗栓塞治疗小肝细胞癌的局限性。一项对手术切除病例的研究。

Limitation of transcatheter arterial chemoembolization using iodized oil for small hepatocellular carcinoma. A study in resected cases.

作者信息

Kuroda C, Sakurai M, Monden M, Marukawa T, Hosoki T, Tokunaga K, Wakasa K, Okamura J, Kozuka T

机构信息

Department of Radiology, Osaka University Medical School, Japan.

出版信息

Cancer. 1991 Jan 1;67(1):81-6. doi: 10.1002/1097-0142(19910101)67:1<81::aid-cncr2820670116>3.0.co;2-h.

DOI:10.1002/1097-0142(19910101)67:1<81::aid-cncr2820670116>3.0.co;2-h
PMID:1845939
Abstract

The radiologic and histologic findings are presented of the resection of 14 small hepatocellular carcinomas (HCC), less than 2 cm in maximum diameter, after transcatheter arterial chemoembolization (TCE) using iodized oil. The effect of TCE on small HCC depended on the morphologic type of the tumors. When no extracapsular invasion of tumor cells occurred, TCE was extremely effective against encapsulated tumors. However, in nine of the 14 resected specimens, viable tumor cells remained in or around the tumor. The authors suggest that small HCC are not always curable with TCE alone and that a multi-disciplinary approach is necessary for patients with small HCC.

摘要

本文呈现了14例最大直径小于2厘米的小肝细胞癌(HCC)在经动脉化疗栓塞(TCE)并使用碘化油后行手术切除的放射学和组织学结果。TCE对小HCC的疗效取决于肿瘤的形态学类型。当肿瘤细胞无包膜外侵犯时,TCE对包膜完整的肿瘤极为有效。然而,在14例切除标本中,有9例在肿瘤内部或周边仍存在存活的肿瘤细胞。作者认为,小HCC仅靠TCE并不总能治愈,对于小HCC患者,多学科治疗方法是必要的。

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