Crotti Daniele, D'Annibale Maria Letizia
Libero professionista in Parassitologia e Microbiologia Medica, Perugia.
Recenti Prog Med. 2008 Feb;99(2):83-8.
The Authors underline the importance to always and correctly investigate also for Campylobacters and related organisms (Clo's) in faeces of humans with enteritis, because prevalent like Salmonella and for surveillance antibiotic resistances; in fact for campylobacteriosis specific therapy is often necessary. Between 2001 and 2005 248 strains of Campylobacter and Clo's were isolated: 225 were C. jejuni (90.7%) and 16 C. coli (6.5%). The recommended antibiotics to use for therapy, for preventing secondary effects too, are erythromycin, ciprofloxacin and tetracycline. Among C. jejuni, resistances towards erithromycine were 6.8% during 2001-02, 6.8% during 2003 and 4.8% during 2004-05; the resistances towards ciprofloxacin were 52.9% during 2001-02, 53.8% during 2003 and 42.9% during 2004-05; the resistances towards tetracycline were 39.2% during 2001-02, 46.2% during 2003 and 50.0% during 2004-05. The strains of C. coli showed less resistances, also in respect of previous our data too. No relevant differences were observed in antibacterial resistances among strains isolated from children and strains isolated from adults.
作者强调，对于患有肠炎的人类粪便中的弯曲杆菌及相关生物体（Clo's）进行全面且正确的调查十分重要，因为它们与沙门氏菌一样普遍存在，且需对其进行抗生素耐药性监测；事实上，弯曲杆菌病通常需要特定治疗。在2001年至2005年期间，共分离出248株弯曲杆菌和Clo's菌株：其中225株为空肠弯曲菌（90.7%），16株为大肠弯曲菌（6.5%）。用于治疗且能预防副作用的推荐抗生素为红霉素、环丙沙星和四环素。在空肠弯曲菌中，2001 - 2002年对红霉素的耐药率为6.8%，2003年为6.8%，2004 - 2005年为4.8%；对环丙沙星的耐药率在2001 - 2002年为52.9%，2003年为53.8%，2004 - 2005年为42.9%；对四环素的耐药率在2001 - 2002年为39.2%，2003年为46.2%，2004 - 2005年为50.0%。大肠弯曲菌菌株的耐药性较低，这与我们之前的数据相符。从儿童分离出的菌株与从成人分离出的菌株在抗菌耐药性方面未观察到显著差异。
