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血流储备分数在评估冠状动脉心肌桥中的局限性。

Limitation of fractional flow reserve in evaluating coronary artery myocardial bridge.

作者信息

Singh Inder M, Subbarao Roopa A, Sadanandan Saihari

机构信息

Vascular Interventions, Krannert Institute of Cardiology, Indiana University, MPC 2, Room D-4078, 1801 North Senate Blvd., Indianapolis, IN 46202-1258, USA.

出版信息

J Invasive Cardiol. 2008 May;20(5):E161-6.

PMID:18460720
Abstract

Symptomatic myocardial bridge is treated with medical therapy, but in refractory cases, percutaneous revascularization has been used. We describe two cases to highlight differences in coronary compression and flow pattern, which make the luminal narrowing associated with a myocardial bridge anatomically and physiologically different from the fixed stenosis of atherosclerotic epicardial disease. Due to these characteristics, evaluating the functional severity of a myocardial bridge using fractional flow reserve as a guide to revascularization may be of limited value. Furthermore, stenting, including drug-eluting stents, may not be the ideal revascularization strategy secondary to a higher risk of in-stent restenosis.

摘要

有症状的心肌桥采用药物治疗,但在难治性病例中,已采用经皮血管重建术。我们描述两例病例以突出冠状动脉压迫和血流模式的差异,这些差异使得与心肌桥相关的管腔狭窄在解剖学和生理学上不同于动脉粥样硬化性心外膜疾病的固定狭窄。由于这些特征,以血流储备分数作为血管重建术指导来评估心肌桥的功能严重程度可能价值有限。此外,包括药物洗脱支架在内的支架置入术可能并非理想的血管重建策略,因为支架内再狭窄风险较高。

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引用本文的文献

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Performing and Interpreting Fractional Flow Reserve Measurements in Clinical Practice: An Expert Consensus Document.临床实践中进行和解读血流储备分数测量:专家共识文件
Interv Cardiol. 2017 Sep;12(2):97-109. doi: 10.15420/icr.2017:13:2.
2
Case of angina pectoris at rest and during effort due to coronary spasm and myocardial bridging.因冠状动脉痉挛和心肌桥导致的静息性心绞痛和劳力性心绞痛病例。
World J Cardiol. 2015 Jun 26;7(6):367-72. doi: 10.4330/wjc.v7.i6.367.
3
Clinical Relevance of Coronary Fractional Flow Reserve: Art-of-state.
冠状动脉血流储备分数的临床相关性:现状
Chin Med J (Engl). 2015 May 20;128(10):1399-406. doi: 10.4103/0366-6999.156805.
4
Angina Relief by Ranolazine Identifies False-Negative SPECT Myocardial Perfusion Scans in Patients with Coronary Disease Demonstrated by Coronary Angiography.通过雷诺嗪缓解心绞痛可识别出经冠状动脉造影证实患有冠心病患者的单光子发射计算机断层扫描(SPECT)心肌灌注扫描假阴性结果。
Int J Angiol. 2014 Sep;23(3):165-70. doi: 10.1055/s-0034-1382290.