接受阿莫西林-克拉维酸治疗的患者进行曲霉半乳甘露聚糖抗原检测（Platelia Aspergillus galactomannan antigen test）时出现的假阳性结果。
False-positive results by the platelia Aspergillus galactomannan antigen test for patients treated with amoxicillin-clavulanate.
作者信息
Zandijk E, Mewis A, Magerman K, Cartuyvels R
机构信息
Department of Internal Medicine, Clinical Laboratory, Virga Jesse Hospital, Hasselt, Belgium.
出版信息
Clin Vaccine Immunol. 2008 Jul;15(7):1132-3. doi: 10.1128/CVI.00022-08. Epub 2008 May 7.
Abstract
The Aspergillus galactomannan test is a valuable tool in the diagnosis of invasive aspergillosis. We hereby report a high rate of false-positive results by the Platelia Aspergillus galactomannan antigen test (Bio-Rad Laboratories) for patients treated with amoxicillin-clavulanate.
摘要
半乳甘露聚糖曲霉检测是侵袭性曲霉病诊断中的一项重要工具。我们在此报告，对于接受阿莫西林-克拉维酸治疗的患者，普立泰半乳甘露聚糖曲霉抗原检测（伯乐公司）出现假阳性结果的比例较高。
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本文引用的文献
1
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J Clin Microbiol. 2004 Nov;42(11):5362-3. doi: 10.1128/JCM.42.11.5362-5363.2004.
2
Treatment with piperacillin-tazobactam and false-positive Aspergillus galactomannan antigen test results for patients with hematological malignancies.
Clin Infect Dis. 2004 Mar 15;38(6):917-20. doi: 10.1086/383148. Epub 2004 Feb 27.
3
False-positive galactomannan platelia Aspergillus test results for patients receiving piperacillin-tazobactam.
Clin Infect Dis. 2004 Mar 15;38(6):913-6. doi: 10.1086/382224. Epub 2004 Feb 27.
4
False positive test for aspergillus antigenemia related to concomitant administration of piperacillin and tazobactam.
N Engl J Med. 2003 Dec 11;349(24):2366-7. doi: 10.1056/NEJM200312113492424.
5
Detection of circulating Aspergillus fumigatus galactomannan: value and limits of the Platelia test for diagnosing invasive aspergillosis.
J Clin Microbiol. 2003 May;41(5):2184-6. doi: 10.1128/JCM.41.5.2184-2186.2003.
6
Surveillance of Aspergillus galactomannan antigenemia for invasive aspergillosis by enzyme-linked immunosorbent assay in neutropenic patients treated for hematological malignancies.
Hematol J. 2000;1(2):111-6. doi: 10.1038/sj.thj.6200009.
7
Aspergillus galactomannan detection in the diagnosis of invasive aspergillosis in cancer patients.
J Clin Oncol. 2002 Apr 1;20(7):1898-906. doi: 10.1200/JCO.2002.07.004.
8
Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus.
Clin Infect Dis. 2002 Jan 1;34(1):7-14. doi: 10.1086/323335. Epub 2001 Nov 26.
9
Screening for circulating galactomannan as a noninvasive diagnostic tool for invasive aspergillosis in prolonged neutropenic patients and stem cell transplantation recipients: a prospective validation.
Blood. 2001 Mar 15;97(6):1604-10. doi: 10.1182/blood.v97.6.1604.
10
Value of antigen detection using an enzyme immunoassay in the diagnosis and prediction of invasive aspergillosis in two adult and pediatric hematology units during a 4-year prospective study.
Cancer. 2001 Jan 15;91(2):311-8. doi: 10.1002/1097-0142(20010115)91:2<311::aid-cncr1003>3.0.co;2-3.
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