Singh Arvind, Al-Reefy Hiba, Hewitt Richard, Kotecha Bhik
Royal National Throat, Nose and Ear Hospital, London, WC1X, UK.
Eur Arch Otorhinolaryngol. 2008 Dec;265(12):1489-94. doi: 10.1007/s00405-008-0685-x. Epub 2008 May 8.
ApneaGraph relies on measuring pressure and airflow simultaneously at different levels in the pharynx identifying the segment of airway obstruction and providing baseline respiratory parameters. This study aims to evaluate ApneaGraph and correlate results with both sleep nasendoscopy and polysomnography. This was a prospective study of 49 patients with snoring and/or obstructive sleep apnoea. Thirty of the these patients underwent a PSG and an ApneaGraph study simultaneously in the Sleep Lab. Nineteen patients attended the day surgery unit and had a sleep nasendoscopy with a 10-min ApneaGraph analysis. Polysomnography was used to validate the ApneaGraph system. There are no significant differences (independent t test, P > 0.15) between ApneaGraph compared to Polysomnography based on the apnoea-hypopnoea index, total number of apnoeic events, average oxygen saturations and maximum desaturation. This suggests that the ApneaGraph can be used to assess OSA. Statistically, there is poor correlation between the two groups (Spearman's rho 0.29). In the cases of discordance, ApneaGraph places greater emphasis on a lower pharyngeal contribution. This unique study analyses the ApneaGraph system in the diagnosis of obstructive sleep apnoea and snoring. It demonstrates the benefits of this new system and highlights certain limitations in localizing the site and level of pharyngeal obstruction in patients with sleep disorders.
呼吸暂停监测仪(ApneaGraph)通过同时测量咽部不同水平的压力和气流,识别气道阻塞部位并提供基线呼吸参数。本研究旨在评估呼吸暂停监测仪,并将结果与睡眠鼻内镜检查和多导睡眠图进行关联。这是一项对49例打鼾和/或阻塞性睡眠呼吸暂停患者的前瞻性研究。其中30例患者在睡眠实验室同时接受了多导睡眠图和呼吸暂停监测仪检查。19例患者前往日间手术单元,进行了睡眠鼻内镜检查,并进行了10分钟的呼吸暂停监测仪分析。多导睡眠图用于验证呼吸暂停监测仪系统。基于呼吸暂停低通气指数、呼吸暂停事件总数、平均血氧饱和度和最大血氧饱和度下降情况,呼吸暂停监测仪与多导睡眠图之间无显著差异(独立t检验,P>0.15)。这表明呼吸暂停监测仪可用于评估阻塞性睡眠呼吸暂停。从统计学角度来看,两组之间的相关性较差(斯皮尔曼等级相关系数为0.29)。在结果不一致的情况下,呼吸暂停监测仪更强调下咽的作用。这项独特的研究分析了呼吸暂停监测仪系统在阻塞性睡眠呼吸暂停和打鼾诊断中的应用。它展示了这个新系统的优势,并突出了在定位睡眠障碍患者咽部阻塞部位和水平方面的某些局限性。