Joo Min J, Lee Todd A, Bartle Brian, van de Graaff William B, Weiss Kevin B
Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Illinois at Chicago, 840 S. Wood St., M/C 719, Chicago, IL 60612, USA.
Lung. 2008 Sep-Oct;186(5):307-12. doi: 10.1007/s00408-008-9095-5. Epub 2008 May 8.
Global Initiative on Chronic Obstructive Lung Disease (GOLD) guidelines recently removed stage 0, a group with symptoms but without airways obstruction, from their severity staging. However, in practice this group may still be diagnosed and medically managed. The aim of this study was to characterize healthcare utilization patterns of chronic obstructive pulmonary disease (COPD) patients by disease severity, focusing on the possible unique attributes of patients who would have been classified as GOLD stage 0. This is a prospective cohort pilot study performed at the Hines Veterans Administration Hospital. One hundred twenty patients with a diagnosis of COPD were enrolled. The participants completed quality-of-life questionnaires and a pulmonary function test. Healthcare utilization data were obtained 1 year prior and 2 years after the enrollment date. Three disease severity groups were defined based on GOLD criteria for comparison [GOLD stage 1-2 (GS 1-2), GOLD stage 3-4 (GS 3-4), and formerly GOLD stage 0 ("at risk")]. The "at risk" group had an average of 14.4 (SD = 30.5) outpatient visits/year and 0.3 (SD = 0.8) hospitalizations/year, which were higher than the other groups, but this was not statistically significant. Respiratory medications were used by 6 (26%), 30 (59%), and 40 (91%) patients from "at risk" to GS 3-4, respectively. Patients in the "at risk" group had a decrement in health status, significant utilization of healthcare services, and were often receiving medications not consistent with guidelines.
慢性阻塞性肺疾病全球倡议(GOLD)指南最近将0期(有症状但无气道阻塞的一组)从其严重程度分期中移除。然而,在实际中,这一组患者仍可能被诊断并接受医学管理。本研究的目的是按疾病严重程度描述慢性阻塞性肺疾病(COPD)患者的医疗服务利用模式,重点关注那些原本会被归类为GOLD 0期患者可能具有的独特特征。这是一项在海因斯退伍军人管理局医院进行的前瞻性队列试点研究。招募了120名诊断为COPD的患者。参与者完成了生活质量问卷和肺功能测试。在入组日期前1年和入组后2年获取医疗服务利用数据。根据GOLD标准定义了三个疾病严重程度组以进行比较[GOLD 1-2期(GS 1-2)、GOLD 3-4期(GS 3-4)和原GOLD 0期(“风险组”)]。“风险组”患者每年平均门诊就诊14.4次(标准差=30.5),住院0.3次(标准差=0.8),高于其他组,但无统计学意义。“风险组”至GS 3-4组分别有6名(26%)、30名(59%)和40名(91%)患者使用呼吸药物。“风险组”患者健康状况下降,医疗服务利用显著,且经常接受不符合指南的药物治疗。