Li Xue-Hu, Qi Huan-Yang, Shi Yan-Ping
Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China.
J Asian Nat Prod Res. 2008 May-Jun;10(5-6):397-402. doi: 10.1080/10286020801966583.
A new dammarane triterpenoid oliganthas A (1) and a new taraxastane triterpenoid oliganthas B (2), as well as five known taraxastane triterpenoids, ptiloepoxide (3), taraxast-20(30)ene-3beta,21alpha-diol (4), 22-oxo-20-taraxasten-3beta-ol (5), taraxast-20-ene-3beta,30-diol (6), and taraxastane-3beta,20alpha-diol (7), were isolated from the whole plant of Saussurea oligantha Franch. Their structures were elucidated by a series of spectroscopic methods. These compounds, especially taraxastanes 2, 5, and 6, exhibited significant antibacterial activity against Actinomyces viscosus ATCC27044.
从少花风毛菊（Saussurea oligantha Franch.）全草中分离得到一个新的达玛烷型三萜寡花素A（1）、一个新的蒲公英赛烷型三萜寡花素B（2）以及五个已知的蒲公英赛烷型三萜类化合物，分别为ptiloepoxide（3）、蒲公英赛-20(30)烯-3β,21α-二醇（4）、22-氧代-20-蒲公英赛烯-3β-醇（5）、蒲公英赛-20-烯-3β,30-二醇（6）和蒲公英赛烷-3β,20α-二醇（7）。通过一系列光谱方法对它们的结构进行了鉴定。这些化合物，尤其是蒲公英赛烷类化合物2、5和6，对粘性放线菌ATCC27044表现出显著的抗菌活性。
