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正常眼和疑似圆锥角膜眼中角膜前表面和后表面高度图的比较及相关性研究

Comparison of and correlation between anterior and posterior corneal elevation maps in normal eyes and keratoconus-suspect eyes.

作者信息

Schlegel Zuzana, Hoang-Xuan Thanh, Gatinel Damien

机构信息

Ophthalmology, Rothschild Foundation, Paris, France.

出版信息

J Cataract Refract Surg. 2008 May;34(5):789-95. doi: 10.1016/j.jcrs.2007.12.036.

DOI:10.1016/j.jcrs.2007.12.036
PMID:18471634
Abstract

PURPOSE

To compare the anterior and posterior corneal elevation maps between keratoconus-suspect eyes and normal eyes.

SETTING

Rothschild Foundation, AP-HP, University Paris VII, Hôpital Bichat Claude Bernard, Paris, France.

METHODS

The anterior and posterior corneal surface elevations were analyzed and compared in 60 normal myopic patients and 48 keratoconus-suspect patients. The anterior and posterior best-fit sphere radii, central and thinnest corneal pachymetries, anterior and posterior aconic shape parameters (aconic radius, aconic asphericity, aconic toricity), and anterior and posterior elevation in the 1.0 mm radius zone were analyzed. The correlations between elevation and aconic shape parameters between the anterior and posterior surfaces were compared.

RESULTS

The mean central and thinnest pachymetry values were significantly lower in keratoconus-suspect eyes (P<.0001). Compared with normal eyes, keratoconus-suspect eyes had significantly increased anterior toricity (P = .0002) and posterior toricity (P<.0001), more negative asphericity (P = .042), and higher posterior elevation (P<.0001). The correlation between aconic toricity and the anterior and posterior corneal surfaces was better in keratoconus-suspect eyes than in normal eyes. Aconic asphericity and apical curvature were less correlated in keratoconus-suspect eyes than in normal eyes.

CONCLUSIONS

The posterior corneal elevation and the corneal thickness values were different in keratoconus-suspect eyes. The correlation between the anterior and posterior corneal aconic shapes was between keratoconus-suspect eyes and normal eyes.

摘要

目的

比较疑似圆锥角膜眼与正常眼的角膜前、后表面高度图。

设置

法国巴黎第七大学巴黎公立医院集团罗思柴尔德基金会比夏特 - 克劳德·贝尔纳医院。

方法

分析并比较60例正常近视患者和48例疑似圆锥角膜患者的角膜前、后表面高度。分析前、后最佳拟合球面半径、中央及最薄角膜厚度、前、后非圆锥形状参数(非圆锥半径、非圆锥非球面性、非圆锥散光性)以及半径1.0 mm区域内的前、后表面高度。比较前、后表面高度与非圆锥形状参数之间的相关性。

结果

疑似圆锥角膜眼的平均中央及最薄角膜厚度值显著更低(P <.0001)。与正常眼相比,疑似圆锥角膜眼的前表面散光性(P =.0002)和后表面散光性(P <.0001)显著增加,非球面性更负(P =.042),后表面高度更高(P <.0001)。疑似圆锥角膜眼中非圆锥散光性与角膜前、后表面的相关性优于正常眼。疑似圆锥角膜眼中非圆锥非球面性与顶点曲率的相关性低于正常眼。

结论

疑似圆锥角膜眼的角膜后表面高度和角膜厚度值不同。角膜前、后非圆锥形状之间的相关性在疑似圆锥角膜眼和正常眼之间存在差异。

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