Keratoconus Unit, Vissum Corporation-Instituto Oftalmologico de Alicante, Departamento de Optica, Universidad de Alicante, Alicante, Spain.
J Cataract Refract Surg. 2010 May;36(5):814-25. doi: 10.1016/j.jcrs.2009.11.012.
To evaluate the corneal volume, pachymetry, and correlation of anterior and posterior corneal shape in subclinical and clinical keratoconus.
Vissum Corporation, Alicante, Spain.
Eyes were placed into 1 of 4 groups as follows: keratoconus 2 (grade II), keratoconus 1 (grade I), subclinical (subclinical keratoconus), and control (normal eyes). All eyes had an ophthalmologic examination including corneal evaluation (curvature, elevation, asphericity, pachymetry, corneal volume) by rotating Scheimpflug imaging (Pentacam). The posterior-anterior corneal power ratio was also calculated.
Seventy-one eyes (51 patients; aged 16 to 64 years) were evaluated. Astigmatism and keratometry of both corneal surfaces were statistically significantly higher in the keratoconus 1 and 2 groups (P<or=.02). Posterior astigmatism was statistically significantly higher in the subclinical group than in the control group (P = .01). A strong correlation (r>or=-0.81) was found between anterior and posterior curvature in the normal and subclinical groups; the correlation was weaker in clinical keratoconus cases (r<or=-0.56). The correlation in astigmatism between the anterior and posterior surface was good in all keratoconus groups (r>or=0.81). The posterior-anterior corneal power ratio was significantly higher in the keratoconus 2 group than in the other groups (P<or=.01). Pachymetric readings were progressively lower in eyes with subclinical, early, or moderate keratoconus (P<.01). The corneal volume was statistically significantly lower in the keratoconus 2 group than in the other groups (P = .04).
The correlation between anterior and posterior corneal curvature was lower in keratoconus, although the correlation between anterior and posterior astigmatism was maintained.
评估亚临床和临床圆锥角膜的角膜体积、角膜厚度和前、后角膜形态的相关性。
西班牙阿利坎特的 Vissum 公司。
将眼睛分为以下 4 组之一：圆锥角膜 2 级（grade II）、圆锥角膜 1 级（grade I）、亚临床（亚临床圆锥角膜）和对照（正常眼）。所有眼睛均进行眼科检查，包括旋转式 Scheimpflug 成像（Pentacam）的角膜评估（曲率、高度、非球性、角膜厚度、角膜体积）。还计算了后-前角膜力比。
共评估了 71 只眼（51 例患者；年龄 16 岁至 64 岁）。圆锥角膜 1 级和 2 级组的角膜表面散光和角膜曲率均有统计学意义上的显著升高（P<0.02）。亚临床组的后向散光显著高于对照组（P=0.01）。在正常组和亚临床组中，前、后曲率之间存在很强的相关性（r>or=-0.81）；在临床圆锥角膜病例中，相关性较弱（r<or=-0.56）。在所有圆锥角膜组中，前、后表面之间的散光相关性均良好（r>or=0.81）。圆锥角膜 2 级组的后-前角膜力比显著高于其他组（P<0.01）。亚临床、早期或中度圆锥角膜的角膜厚度读数逐渐降低（P<.01）。圆锥角膜 2 级组的角膜体积显著低于其他组（P=0.04）。
虽然前、后散光的相关性保持不变，但圆锥角膜的前、后角膜曲率相关性较低。
