Austin Peter C
Institute for Clinical Evaluative Sciences, Toronto, Ontario.
BMC Med Res Methodol. 2008 May 12;8:30. doi: 10.1186/1471-2288-8-30.
There is a growing trend towards the production of "hospital report-cards" in which hospitals with higher than acceptable mortality rates are identified. Several commentators have advocated for the use of Bayesian hierarchical models in provider profiling. Several researchers have shown that some degree of misclassification will result when hospital report cards are produced. The impact of misclassifying hospital performance can be quantified using different loss functions.
We propose several families of loss functions for hospital report cards and then develop Bayes rules for these families of loss functions. The resultant Bayes rules minimize the expected loss arising from misclassifying hospital performance. We develop Bayes rules for generalized 1-0 loss functions, generalized absolute error loss functions, and for generalized squared error loss functions. We then illustrate the application of these decision rules on a sample of 19,757 patients hospitalized with an acute myocardial infarction at 163 hospitals.
We found that the number of hospitals classified as having higher than acceptable mortality is affected by the relative penalty assigned to false negatives compared to false positives. However, the choice of loss function family had a lesser impact upon which hospitals were identified as having higher than acceptable mortality.
The design of hospital report cards can be placed in a decision-theoretic framework. This allows researchers to minimize costs arising from the misclassification of hospitals. The choice of loss function can affect the classification of a small number of hospitals.
制作“医院成绩单”的趋势日益增长,其中会识别出死亡率高于可接受水平的医院。一些评论家主张在医疗服务提供者概况分析中使用贝叶斯分层模型。一些研究人员表明,在制作医院成绩单时会出现一定程度的错误分类。可以使用不同的损失函数来量化医院绩效错误分类的影响。
我们为医院成绩单提出了几类损失函数,然后为这些损失函数族制定贝叶斯规则。由此产生的贝叶斯规则将医院绩效错误分类所产生的预期损失降至最低。我们为广义0-1损失函数、广义绝对误差损失函数和广义平方误差损失函数制定贝叶斯规则。然后,我们在163家医院的19757例急性心肌梗死住院患者样本中说明了这些决策规则的应用。
我们发现,与假阳性相比,被归类为死亡率高于可接受水平的医院数量受分配给假阴性的相对惩罚的影响。然而,损失函数族的选择对哪些医院被识别为死亡率高于可接受水平的影响较小。
医院成绩单的设计可以置于决策理论框架中。这使研究人员能够将医院错误分类产生的成本降至最低。损失函数的选择可能会影响少数医院的分类。