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同时对多个二分类指标进行提供者分析时,比较多元响应贝叶斯随机效应逻辑回归模型与潜在变量项目反应理论模型。

Comparing a multivariate response Bayesian random effects logistic regression model with a latent variable item response theory model for provider profiling on multiple binary indicators simultaneously.

机构信息

ICES, Toronto, Canada.

Institute of Health Management, Policy and Evaluation, University of Toronto, Toronto, Canada.

出版信息

Stat Med. 2020 Apr 30;39(9):1390-1406. doi: 10.1002/sim.8484. Epub 2020 Feb 11.

DOI:10.1002/sim.8484
PMID:32043653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7187268/
Abstract

Provider profiling entails comparing the performance of hospitals on indicators of quality of care. Many common indicators of healthcare quality are binary (eg, short-term mortality, use of appropriate medications). Typically, provider profiling examines the variation in each indicator in isolation across hospitals. We developed Bayesian multivariate response random effects logistic regression models that allow one to simultaneously examine variation and covariation in multiple binary indicators across hospitals. Use of this model allows for (i) determining the probability that a hospital has poor performance on a single indicator; (ii) determining the probability that a hospital has poor performance on multiple indicators simultaneously; (iii) determining, by using the Mahalanobis distance, how far the performance of a given hospital is from that of an average hospital. We illustrate the utility of the method by applying it to 10 881 patients hospitalized with acute myocardial infarction at 102 hospitals. We considered six binary patient-level indicators of quality of care: use of reperfusion, assessment of left ventricular ejection fraction, measurement of cardiac troponins, use of acetylsalicylic acid within 6 hours of hospital arrival, use of beta-blockers within 12 hours of hospital arrival, and survival to 30 days after hospital admission. When considering the five measures evaluating processes of care, we found that there was a strong correlation between a hospital's performance on one indicator and its performance on a second indicator for five of the 10 possible comparisons. We compared inferences made using this approach with those obtained using a latent variable item response theory model.

摘要

供应商分析需要比较医院在护理质量指标上的表现。许多常见的医疗质量指标都是二进制的(例如,短期死亡率,适当药物的使用)。通常,供应商分析会单独检查每个指标在各个医院之间的差异。我们开发了贝叶斯多元响应随机效应逻辑回归模型,该模型允许同时检查多个医院中多个二进制指标的变化和协变。使用这种模型可以:(i)确定医院在单个指标上表现不佳的概率;(ii)确定医院在多个指标上同时表现不佳的概率;(iii)通过使用马氏距离,确定给定医院的表现与平均医院的距离。我们通过将其应用于 102 家医院的 10881 名急性心肌梗死住院患者来说明该方法的实用性。我们考虑了六个患者层面的护理质量二进制指标:再灌注的使用、左心室射血分数的评估、心肌肌钙蛋白的测量、入院后 6 小时内使用乙酰水杨酸、入院后 12 小时内使用β受体阻滞剂,以及入院后 30 天的生存情况。在考虑评估护理过程的五项措施时,我们发现,在十个可能的比较中,有五个比较中,医院在一个指标上的表现与其在第二个指标上的表现之间存在很强的相关性。我们将使用这种方法得出的推论与使用潜在变量项目反应理论模型得出的推论进行了比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cd8/7187268/7eab18c5bd77/SIM-39-1390-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cd8/7187268/5f90ca4cb049/SIM-39-1390-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cd8/7187268/0eccd5c9a4c4/SIM-39-1390-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cd8/7187268/a7d7b3c1af0b/SIM-39-1390-g003.jpg
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