Paemeleire Koen, Evers Stefan, Goadsby Peter J
Headache Clinic, Department of Neurology, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.
Curr Pain Headache Rep. 2008 Apr;12(2):122-7. doi: 10.1007/s11916-008-0023-4.
Cluster headache (CH) is associated with the most severe pain of the primary headache disorders. Barriers to optimal care include misdiagnosis, diagnostic delay, undertreatment, and mismanagement. Medication-overuse headache (MOH) may further complicate CH and may present as increased CH frequency or development of a background headache, which may be featureless or have some migrainous quality. A personal or familial history of migraine appears to be strongly associated with the development of MOH in CH, at least with the phenotype of background headache. Patients with CH, especially those with a personal and/or family history of migraine, must be carefully monitored for MOH, and medication withdrawal should be considered if a CH patient presents with features of MOH.
丛集性头痛（CH）与原发性头痛疾病中最严重的疼痛相关。最佳治疗的障碍包括误诊、诊断延误、治疗不足和管理不当。药物过量使用性头痛（MOH）可能会使CH进一步复杂化，可能表现为CH发作频率增加或出现背景性头痛，后者可能没有特征或具有一些偏头痛的性质。偏头痛的个人或家族史似乎与CH中MOH的发生密切相关，至少与背景性头痛的表型有关。CH患者，尤其是有偏头痛个人和/或家族史的患者，必须密切监测是否发生MOH，如果CH患者出现MOH的特征，应考虑停药。
