Bacteria in the intestine, helpful residents or enemies from within?
作者信息
Canny Geraldine O, McCormick Beth A
机构信息
Mucosal Immunity Laboratory, Department of Gynecology, Obstetrics and Medical Genetics, Central University Hospital of Vaud, Lausanne 1011, Switzerland.
出版信息
Infect Immun. 2008 Aug;76(8):3360-73. doi: 10.1128/IAI.00187-08. Epub 2008 May 12.
Abstract
摘要
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Bacteria in the intestine, helpful residents or enemies from within?肠道中的细菌，是有益的居民还是体内的敌人？
Infect Immun. 2008 Aug;76(8):3360-73. doi: 10.1128/IAI.00187-08. Epub 2008 May 12.
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Some Medical and other Aspects of Bacterial Chemistry: (Section of Pathology).细菌化学的一些医学及其他方面：（病理学部分）
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The enteropathogenic E. coli effector EspB facilitates microvillus effacing and antiphagocytosis by inhibiting myosin function.肠道致病性大肠杆菌效应蛋白EspB通过抑制肌球蛋白功能促进微绒毛消失和抗吞噬作用。
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Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease.全基因组关联扫描显示，两个自噬基因，即自噬相关基因16样蛋白1（ATG16L1）和免疫相关鸟苷三磷酸酶家族M成员1（IRGM），与克罗恩病显著相关。
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Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species.共生细菌通过产生活性氧来调节依赖cullin的信号传导。
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Unveiling the roles of autophagy in innate and adaptive immunity.揭示自噬在固有免疫和适应性免疫中的作用。
Nat Rev Immunol. 2007 Oct;7(10):767-77. doi: 10.1038/nri2161.
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Identification of the Salmonella enterica serotype typhimurium SipA domain responsible for inducing neutrophil recruitment across the intestinal epithelium.鉴定肠炎沙门氏菌鼠伤寒血清型中负责诱导中性粒细胞穿过肠上皮募集的SipA结构域。
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Innate and adaptive immunity through autophagy.通过自噬实现的固有免疫和适应性免疫。
Immunity. 2007 Jul;27(1):11-21. doi: 10.1016/j.immuni.2007.07.004.
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