Ptitsina S N, Bobrov V I, Borisov M M
Antibiot Khimioter. 2007;52(6):13-6.
Therapeutic activity, pharmacokinetic and bioavailability on animals (inbred white mouse, rabbits) were evaluated for Ofloxacin-PhPO and Pefloxacin-genova in comparison with innovator products--Tarivid and Abaktal. The results of the experiments demonstrate that investigated generics by their therapeutic efficacy in animals and by bioavailability are similar to original products.
对氧氟沙星-磷酰氧（Ofloxacin-PhPO）和培氟沙星-热诺瓦（Pefloxacin-genova）与创新产品——泰利必妥（Tarivid）和甲磺酸培氟沙星（Abaktal）相比，在动物（近交系小白鼠、兔子）身上进行了治疗活性、药代动力学和生物利用度评估。实验结果表明，所研究的仿制药在动物体内的治疗效果和生物利用度与原产品相似。
