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腹腔灌洗中良性多囊性腹膜间皮瘤的细胞学检查

Cytology of benign multicystic peritoneal mesothelioma in peritoneal washings.

作者信息

Assaly M, Bongiovanni M, Kumar N, Egger J-F, Pelte M-F, Genevay M, Finci V, Tschanz E, Pache J-C

机构信息

Department of Pathology, Geneva University Hospital, Geneva, Switzerland.

出版信息

Cytopathology. 2008 Aug;19(4):224-8. doi: 10.1111/j.1365-2303.2007.00489.x. Epub 2008 May 9.

Abstract

OBJECTIVE

To describe the cytological aspect of peritoneal washings in benign multicystic peritoneal mesothelioma (BMPM).

METHODS

Three peritoneal washing specimens stained by standard cytological and histological procedures and analysed by light microscopy.

RESULTS

The specimens showed an abundance of monomorphous mesothelial cells devoid of atypia or mitoses. The mesothelial cells were calretinin positive. They also showed numerous squamous metaplastic cells arranged in flat sheets or isolated cells. The background contained some inflammatory cells.

CONCLUSION

The combination of cytology of the peritoneal washing, histology (cell block and surgical specimen) and clinical history allow differentiation of BMPM from other cystic lesions (cystic lymphangioma and malignant mesothelioma).

摘要

目的

描述良性多囊性腹膜间皮瘤(BMPM)中腹腔冲洗液的细胞学特征。

方法

对3份腹腔冲洗液标本采用标准细胞学和组织学方法染色,并通过光学显微镜进行分析。

结果

标本显示大量形态单一的间皮细胞,无异型性或有丝分裂象。间皮细胞钙视网膜蛋白呈阳性。还可见大量鳞状化生细胞,呈扁平片状或单个细胞分布。背景中含有一些炎性细胞。

结论

腹腔冲洗液细胞学、组织学(细胞块和手术标本)及临床病史相结合,有助于将BMPM与其他囊性病变(囊性淋巴管瘤和恶性间皮瘤)区分开来。

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