一名肝移植受者发生的淋巴皮肤型诺卡菌病和皮肤暗色丝孢霉病。
Lymphocutaneous nocardiosis and cutaneous pheohyphomycosis in a liver transplant recipient.
作者信息
Parra Isabel Hidalgo, Galimberti Ricardo, Galimberti Gastón, Guanella Barbara, Kowalczuk Alicia
机构信息
Dermatology Department, Italian Hospital, Buenos Aires, Argentina.
出版信息
Int J Dermatol. 2008 Jun;47(6):571-4. doi: 10.1111/j.1365-4632.2008.03728.x.
BACKGROUND
Infections are the leading cause of morbidity and mortality in transplanted patients. The increasing number of immunocompromised patients has not only augmented infections by specific pathogens, but also by opportunistic microbial agents.
METHODS
A mixed cutaneous infection caused by Nocardia brasiliensis and Exophiala jeanselmei is reported in a liver transplant patient.
RESULTS
The cutaneous lesions were painful nodules which drained purulent material. They were located on the right lower limb, with lymphadenopathies in the groin.
CONCLUSIONS
The patient was treated with itraconazole (600 mg/day) plus trimethoprim (1600 mg/day)-sulfamethoxazole (320 mg/day) for 8 weeks, with complete remission of the lesions.
背景
感染是移植患者发病和死亡的主要原因。免疫功能低下患者数量的增加不仅增加了特定病原体引起的感染，也增加了机会性微生物病原体引起的感染。
方法
报告了1例肝移植患者发生的由巴西奴卡菌和吉氏外瓶霉引起的混合性皮肤感染。
结果
皮肤损害为排出脓性物质的疼痛性结节。位于右下肢，腹股沟有淋巴结病。
结论
患者接受伊曲康唑（600毫克/天）加甲氧苄啶（1600毫克/天）-磺胺甲恶唑（320毫克/天）治疗8周，皮损完全缓解。
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