Wilson J E, Kiselanova N, Stevens Q, Lutz R, Mandler T, Tran Z V, Wischmeyer P E
Department of Anaesthesia, University of Colorado Health Sciences Center, Denver, Colorado, USA.
Anaesthesia. 2008 Jun;63(6):616-20. doi: 10.1111/j.1365-2044.2008.05444.x.
This study aims to assess the prevalence and outcomes of inhalational anaesthetic abuse among anaesthesia training programmes. Online surveys were completed by chairpersons of academic anaesthesia training programmes in the United States. The response rate was 84% (106/126 programmes). Twenty-two percent of the departments had had at least one incident of inhalational anaesthetic abuse. Forty-eight percent (15/31) of the persons abusing inhalational anaesthetics were sent for rehabilitation. Only 22% (7/31) of those found to be abusing inhalational anaesthetics were ultimately able to return successfully to anaesthesia practice with sustained recovery. The mortality rate among individuals found abusing inhalational anaesthetics was 26% (8/31). The majority of the anaesthesia departments (97/104, 93%) did not have any pharmacy accounting of inhalational anaesthetics. This is the first published survey of inhalational anaesthesia abuse. Inhalational anaesthetic abuse should be considered in at-risk individuals or those with a history of substance abuse. The concern about substance abuse is not unique to American anaesthetists. Countries around the world deal with similar substance abuse issues.
本研究旨在评估麻醉培训项目中吸入性麻醉剂滥用的发生率及后果。美国学术性麻醉培训项目的负责人完成了在线调查。回复率为84%（106/126个项目）。22%的科室至少发生过一起吸入性麻醉剂滥用事件。滥用吸入性麻醉剂的人员中有48%（15/31）被送去康复治疗。在被发现滥用吸入性麻醉剂的人员中，最终只有22%（7/31）能够成功恢复并持续康复，重返麻醉工作岗位。被发现滥用吸入性麻醉剂的人员死亡率为26%（8/31）。大多数麻醉科室（97/104，93%）没有对吸入性麻醉剂进行任何药房核算。这是首次发表的关于吸入性麻醉剂滥用的调查。对于高危个体或有药物滥用史的个体，应考虑存在吸入性麻醉剂滥用的情况。对药物滥用的担忧并非美国麻醉医生所独有。世界各国都面临类似的药物滥用问题。
