Futcher Bruce
Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794, USA.
Dev Cell. 2008 May;14(5):644-5. doi: 10.1016/j.devcel.2008.04.009.
In a recent issue of Cell, Carlile and Amon examine the regulation of four budding yeast B-type cyclins, crucial for regulating and distinguishing meoisis I and meoisis II divisions, and find a surprising diversity of behaviors and modes of regulation. In particular, Clb3 is regulated by a striking translational repression specific to meoisis I.
在最近一期的《细胞》杂志中,卡利尔和阿蒙研究了四种芽殖酵母B型细胞周期蛋白的调控机制,这些蛋白对于调控和区分减数分裂I和减数分裂II至关重要,并发现了令人惊讶的行为多样性和调控模式。特别是,Clb3受一种特异于减数分裂I的显著翻译抑制调控。