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急性卒中成像研究路线图。

Acute stroke imaging research roadmap.

作者信息

Wintermark Max, Albers Gregory W, Alexandrov Andrei V, Alger Jeffry R, Bammer Roland, Baron Jean-Claude, Davis Stephen, Demaerschalk Bart M, Derdeyn Colin P, Donnan Geoffrey A, Eastwood James D, Fiebach Jochen B, Fisher Marc, Furie Karen L, Goldmakher Gregory V, Hacke Werner, Kidwell Chelsea S, Kloska Stephan P, Köhrmann Martin, Koroshetz Walter, Lee Ting-Yim, Lees Kennedy R, Lev Michael H, Liebeskind David S, Ostergaard Leif, Powers William J, Provenzale James, Schellinger Peter, Silbergleit Robert, Sorensen Alma Gregory, Wardlaw Joanna, Wu Ona, Warach Steven

机构信息

Department of Radiology, University of California, San Francisco, CA 94143-0628, USA.

出版信息

AJNR Am J Neuroradiol. 2008 May;29(5):e23-30. doi: 10.1161/STROKEAHA.107.512319.

DOI:10.1161/STROKEAHA.107.512319
PMID:18477656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2716734/
Abstract

The recent "Advanced Neuroimaging for Acute Stroke Treatment" meeting on September 7 and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, emergency physicians, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), industry representatives, and members of the US Food and Drug Administration (FDA) to discuss the role of advanced neuroimaging in acute stroke treatment. The goals of the meeting were to assess state-of-the-art practice in terms of acute stroke imaging research and to propose specific recommendations regarding: (1) the standardization of perfusion and penumbral imaging techniques, (2) the validation of the accuracy and clinical utility of imaging markers of the ischemic penumbra, (3) the validation of imaging biomarkers relevant to clinical outcomes, and (4) the creation of a central repository to achieve these goals. The present article summarizes these recommendations and examines practical steps to achieve them.

摘要

2007年9月7日至8日在华盛顿特区召开的近期“急性卒中治疗的先进神经影像学”会议,汇聚了卒中神经科医生、神经放射科医生、急诊医生、神经影像学研究科学家、国立神经疾病与卒中研究所(NINDS)、国立生物医学成像和生物工程研究所(NIBIB)的成员、行业代表以及美国食品药品监督管理局(FDA)的成员,共同探讨先进神经影像学在急性卒中治疗中的作用。会议的目标是评估急性卒中成像研究方面的最新实践,并就以下方面提出具体建议:(1)灌注和半暗带成像技术的标准化;(2)缺血半暗带成像标志物准确性和临床实用性的验证;(3)与临床结局相关的成像生物标志物的验证;(4)建立一个中央储存库以实现这些目标。本文总结了这些建议并探讨了实现这些建议的实际步骤。

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