Qu Lijun, Wang Xinghuan, Huang Xing, Zhang Yanqing, Zeng Xiao
The Second Clinic College of Wuhan University, Wuhan, China.
Urol Int. 2008;80(3):292-5. doi: 10.1159/000127344. Epub 2008 May 14.
To compare the hemostatic properties of transurethral plasmakinetic resection of the prostate (PKRP) and standard transurethral resection of the prostate (TURP) ex vivo, as perioperative bleeding is still regarded as one of the major complications of transurethral prostatectomy.
Isolated normal saline (NS)-perfused porcine kidneys were used to determine the hemostatic efficacy of PKRP and TURP. The perfusion fluid loss was semiquantitatively measured in relation to tissue ablation for the two techniques and specimens were evaluated histologically.
The PKRP group had a significantly smaller loss of NS than the TURP group (4.16 +/- 1.25 and 6.39 +/- 1.05 g/min, respectively, p < 0.01). Compared with the measurements with TURP, the depths of the coagulation zones with PKRP were significantly larger (225.09 +/- 35.77 and 146.84 +/- 18.91 microm, respectively, p< 0.01).
PKRP ex vivo was associated with significantly better hemostasis than TURP.
由于围手术期出血仍被视为经尿道前列腺切除术的主要并发症之一,因此在体外比较经尿道前列腺等离子双极电切术(PKRP)和标准经尿道前列腺切除术(TURP)的止血特性。
使用分离的生理盐水(NS)灌注猪肾来测定PKRP和TURP的止血效果。针对这两种技术,半定量测量与组织切除相关的灌注液损失,并对标本进行组织学评估。
PKRP组的NS损失明显小于TURP组(分别为4.16±1.25和6.39±1.05克/分钟,p<0.01)。与TURP测量结果相比,PKRP的凝固区深度明显更大(分别为225.09±35.77和146.84±18.91微米,p<0.01)。
体外实验中,PKRP的止血效果明显优于TURP。