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使用等离子动能进行经尿道前列腺汽化术的安全性和有效性:长期结果

Safety and efficacy of transurethral vaporization of the prostate using plasma kinetic energy: Long-term outcome.

作者信息

Talat Mahmoud, Abdrabuh Abdrabuh Mostafa, Elhelali Mohammed, Elsotohi Ibrahim, Eleweedy Sayed

机构信息

Department of Urology, Al-Azhar University Hospitals, Cairo, Egypt.

出版信息

Urol Ann. 2019 Apr-Jun;11(2):175-179. doi: 10.4103/UA.UA_76_18.

Abstract

OBJECTIVE

The objective of this study was to assess the long-term efficacy and safety of plasma kinetic vaporization (PKVP) of the prostate for symptomatic benign prostatic hyperplasia.

PATIENTS AND METHODS

Twenty-one patients had been enrolled in this study at Al-Azhar University Hospitals to evaluate their long-term follow-up after PKVP. The outcome was evaluated using the International Prostate Symptom Score (IPSS), quality of life (QOL), peak urinary flow rate (Q), postvoiding residual (PVR) of urine, prostate volume, prostate-specific antigen (PSA) level, and long-term complications of the surgery.

RESULTS

Preoperatively, IPSS was 22.14 ± 2.22, QOL score was 4.90 ± 0.54, Q was 8.97 ± 2.49 ml/s, PVR was 138.5 ± 56.5 ml, prostate volume was 64.32 ± 11.16 ml, and PSA level was 4.18 ± 1.95 ng/ml. Two years' post-PKVP, IPSS decreased to 8.57 ± 5.55, QOL score decreased to 1.90 ± 1.22, Q increased to 17.17 ± 7.91 ml/s, PVR decreased to 38.81 ± 59.54 ml, prostate volume decreased to 22.45 ± 7.22 ml, and PSA level decreased to 1.59 ± 0.74 ng/ml. One patient (4.8%) developed bulbar urethral stricture, 1 (4.8%) developed bladder neck contracture, and 1 (4.8%) developed meatal stenosis. Erectile dysfunction was reported by two out of 12 patients who were sexually potent before surgery, and retrograde ejaculation was reported by 10 patients (83%).

CONCLUSION

The present study has demonstrated satisfactory good efficacy and safety of PKVP on the long term.

摘要

目的

本研究的目的是评估前列腺等离子体动力汽化术(PKVP)治疗有症状良性前列腺增生症的长期疗效和安全性。

患者与方法

21例患者在爱资哈尔大学医院参与本研究,以评估PKVP术后的长期随访情况。使用国际前列腺症状评分(IPSS)、生活质量(QOL)、最大尿流率(Q)、残余尿量(PVR)、前列腺体积、前列腺特异性抗原(PSA)水平以及手术的长期并发症来评估结果。

结果

术前,IPSS为22.14±2.22,QOL评分为4.90±0.54,Q为8.97±2.49 ml/s,PVR为138.5±56.5 ml,前列腺体积为64.32±11.16 ml,PSA水平为4.18±1.95 ng/ml。PKVP术后两年,IPSS降至8.57±5.55,QOL评分降至1.90±1.22,Q升至17.17±7.91 ml/s,PVR降至38.81±59.54 ml,前列腺体积降至22.45±7.22 ml,PSA水平降至1.59±0.74 ng/ml。1例患者(4.8%)发生球部尿道狭窄,1例(4.8%)发生膀胱颈挛缩,1例(4.8%)发生尿道口狭窄。12例术前有性功能的患者中有2例报告出现勃起功能障碍,10例患者(83%)报告有逆行射精。

结论

本研究表明PKVP长期疗效和安全性良好,令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/456f/6476202/524f208bd00b/UA-11-175-g001.jpg

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