Shen W C, Yang C F, Chang C Y, Ho W L
Department of Radiology, Veterans General Hospital-Taichung.
Zhonghua Yi Xue Za Zhi (Taipei). 1991 Feb;47(2):91-100.
CT scan shows some relatively large white matter pathways such as corpus callosum or internal capsule, while MRI provides more sophisticated display of cerebral white matter pathways, based partly on difference in the water content, which improves contrast resolution of structures that cannot be appreciated on CT scanning. The white matter shows slightly high signal intensity in T1WI as compared with the peripheral gray matter. In contrast, it is relatively low signal intensity in long TR sequence. The signal intensity is correlated with myelination, density of myelin fibers and possibly iron deposition. In this study, we collected data on 30 patient, aged from 3 to 60 years average 38 years of normal MRI study of the brain. We routinely obtained T1 Weighted image (T1WI, TR/TE 500-600/20 msec), dual echoes image of proton density image (PDI, TR/TE 2000-3000/20 msec), T2 weighted image (T2WI, TR/TE 2000-3000/80-120 msec), in axial and coronal sections. In some cases sagittal section was also imaged. We identified the white matter pathways based on the data from the axial and coronal sections of 2 autopsy specimens. We also consulted several textbooks and literature reviews of gross and MRI anatomy. The following white matter pathways could be clearly observed on MRI: 1. Projection fibers: corona radiata and internal capsule; 2. Commissural fibers: corpus callosum and anterior commissure; 3. Associated fibers: superior occipito-frontal fasciculus, superior longitudinal fasciculus, ucinate fasciculus, cingulum bundle, optic radiation fornix and mammillothalamic tract.