Bonnier Christine
Service de neurologie pédiatrique, Cliniques universitaires Saint-Luc, Brussels, Belgium.
Acta Paediatr. 2008 Jul;97(7):853-8. doi: 10.1111/j.1651-2227.2008.00834.x. Epub 2008 May 14.
The term 'early intervention' designates educational and neuroprotection strategies aimed at enhancing brain development. Early educational strategies seek to take advantage of cerebral plasticity. Neuroprotection, a term initially used to characterize substances capable of preventing cell death, now encompasses all interventions that promote normal development and prevent disabilities, including organisational, therapeutic and environment-modifying measures, such as early stimulation programs. Early stimulation programs were first devised in the United States for vulnerable children in low-income families; positive effects were recorded regarding school failure rates and social problems. Programs have also been implemented in several countries for premature infants and low-birth-weight infants, who are at high risk for neurodevelopmental abnormalities. The programs target the child, the parents or both. The best evaluated programs are the NIDCAP (Newborn Individualized Developmental Care and Assessment Program) in Sweden for babies<1500 g in neonatal intensive care units and the longitudinal multisite program IHDP (Infant Health and Development Program) created in the United States for infants<37 weeks or <2500 g.
Although the NIDCAP and the IHDP targeted different populations, they produced similar effects in several regards: efficacy was greatest with programs involving both the parents and the child; long-term stimulation improved cognitive outcomes and child-parent interactions; cognition showed greater improvements than motor skills and larger benefits were obtained in families that combined several risk factors including low education attainment by the mothers.
“早期干预”一词指旨在促进大脑发育的教育和神经保护策略。早期教育策略试图利用大脑可塑性。神经保护最初用于描述能够预防细胞死亡的物质,现在涵盖所有促进正常发育和预防残疾的干预措施,包括组织、治疗和环境改善措施,如早期刺激计划。早期刺激计划最初是在美国为低收入家庭中的弱势儿童设计的;在学校失败率和社会问题方面记录到了积极效果。在几个国家也为早产儿和低体重儿实施了相关计划,这些婴儿有神经发育异常的高风险。这些计划针对儿童、父母或两者。评估最好的计划是瑞典针对新生儿重症监护病房中体重<1500克婴儿的NIDCAP(新生儿个体化发育护理与评估计划),以及美国为孕周<37周或体重<2500克婴儿创建的纵向多地点计划IHDP(婴儿健康与发育计划)。
尽管NIDCAP和IHDP针对不同人群,但它们在几个方面产生了相似的效果:涉及父母和儿童的计划效果最佳;长期刺激改善了认知结果和亲子互动;认知方面的改善比运动技能更明显,在包括母亲教育程度低等多种风险因素并存的家庭中获得的益处更大。