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腰椎原发性脂肪肉瘤

Primary liposarcoma of the lumbar spine.

作者信息

Lmejjati Mohamed, Loqa Chakir, Haddi Mustapha, Hakkou Mohamed, BenAli Said Ait

机构信息

Department of Neurosurgery, University Hospital CHU Mohammed VI Marrakesh, Marrakesh, Morocco.

出版信息

Joint Bone Spine. 2008 Jul;75(4):482-5. doi: 10.1016/j.jbspin.2007.06.017. Epub 2008 May 19.

Abstract

BACKGROUND

We describe a rare case of the cauda equina syndrome caused by a primary pleomorphic liposarcoma of the lumbar spine.

CASE REPORT

A 35-year-old man presented a 2-month history of back pain and slowly progressive weakness of lower limbs without sphincter dysfunction. It had a laminectomy for a supposed disc herniation three years previously. A diagnosis of recurrence hernia or fibrosis was discussed.

RESULTS

Magnetic Resonance Imaging (MRI) and CT scan of the lumbar vertebral column shows diffuse involvement of L4/L5 vertebral bodies, and an intradural lesion surrounding the nerve roots of cauda equina. The tumor occupied almost the whole width of the spinal canal. The diagnosis of plasmocytoma or metastasis was advocated and the patient was managed by an extended posterior approach in emergency. Histopathological findings revealed a pleomorphic liposarcoma. The patient received a course of radiotherapy and unfortunately he died at 3 months follow-up.

CONCLUSION

In spite of his unusual location in the spine, pleomorphic liposarcoma should be considered in the differential diagnosis of primary spinal tumors.

摘要

背景

我们描述了一例罕见的由腰椎原发性多形性脂肪肉瘤引起的马尾综合征病例。

病例报告

一名35岁男性,有2个月的背痛病史,下肢进行性无力且无括约肌功能障碍。三年前因疑似椎间盘突出症接受了椎板切除术。曾讨论过复发性疝或纤维化的诊断。

结果

腰椎磁共振成像(MRI)和CT扫描显示L4/L5椎体弥漫性受累,马尾神经根周围有硬膜内病变。肿瘤几乎占据了椎管的整个宽度。有人主张诊断为浆细胞瘤或转移瘤,患者在急诊时接受了扩大后路手术。组织病理学检查结果显示为多形性脂肪肉瘤。患者接受了一个疗程的放疗,但不幸的是,在随访3个月时死亡。

结论

尽管多形性脂肪肉瘤在脊柱中的位置不常见,但在原发性脊柱肿瘤的鉴别诊断中仍应考虑到。

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