Rovlias Aristedis, Balanika Alexia, Nomikos Alexandros, Melissaris Savas
Department of Neurosurgery, Asclepeion General Hospital of Voula, Athens, Greece.
Department of Computed Tomography, Asclepeion General Hospital of Voula, Athens, Greece.
J Neurosci Rural Pract. 2017 Aug;8(Suppl 1):S120-S122. doi: 10.4103/jnrp.jnrp_99_17.
Liposarcoma, one of the most common soft-tissue sarcomas, originates from primitive mesenchymal cells, and its diagnostic criteria have been well established. Myxoid liposarcoma is the second most common histological subtype, occurring more frequently during the fourth and fifth decades of life. There are only a few sporadic published cases of spinal liposarcomas, whatever primary or metastatic. We describe an unusual case of primary myxoid liposarcoma of the thoracic spine in a 79-year-old male, presented with a 2-month history of intractable dorsal pain and progressive weakness of lower limbs. Surgical treatment was performed with wide tumor resection, spinal cord decompression, and posterior instrumentation complemented by radiotherapy. Only one other case has been reported with this spinal localization in the literature. Despite its rarity, myxoid liposarcoma should be considered in the differential diagnosis of primary tumors of the thoracic spine.
脂肪肉瘤是最常见的软组织肉瘤之一，起源于原始间充质细胞，其诊断标准已明确确立。黏液样脂肪肉瘤是第二常见的组织学亚型，在40至50岁之间更为常见。无论原发性还是转移性的脊柱脂肪肉瘤，仅有少数散发性病例报道。我们描述了一例79岁男性胸椎原发性黏液样脂肪肉瘤的罕见病例，该患者有2个月顽固性背痛和下肢进行性无力的病史。手术采用广泛肿瘤切除、脊髓减压和后路内固定，并辅以放疗。文献中仅报道过另一例该脊柱定位的病例。尽管罕见，但在胸椎原发性肿瘤的鉴别诊断中应考虑黏液样脂肪肉瘤。
