Lindequist S, Justesen P, Larsen C, Rasmussen F
Department of Diagnostic Radiology, Odense University Hospital, Denmark.
Radiology. 1991 Apr;179(1):69-74. doi: 10.1148/radiology.179.1.1848715.
In a prospective randomized study of 417 patients, side effects and complications of contrast media and the diagnostic quality of images obtained after hysterosalpingography (HSG) were evaluated after use of diatrizoate meglumine (104 patients), ioxaglate (105 patients), iohexol (105 patients), or ethiodized poppy-seed oil (103 patients). The authors detected no differences among these groups in the prevalence of pain during HSG. The prevalence of lower abdominal pain and vaginal bleeding after HSG was significantly lower in the group that received ethiodized poppy-seed oil than in the three other groups. The prevalence of pelvic infection or inflammation was significantly lower with ethiodized poppy-seed oil than with water-soluble media. All contrast media provided acceptable diagnostic image quality with regard to fallopian tubes, peritoneal spill, and intraperitoneal distribution. Visualization of the uterine cavity and ampullary rugae was significantly better with water-soluble media than with ethiodized poppy-seed oil, which was associated with a high conception rate and which the authors consider preferable for HSG.
在一项针对417例患者的前瞻性随机研究中，对使用泛影葡胺（104例患者）、碘克沙醇（105例患者）、碘海醇（105例患者）或乙碘油（103例患者）后造影剂的副作用和并发症以及子宫输卵管造影（HSG）后获得的图像诊断质量进行了评估。作者发现这些组在HSG期间疼痛的发生率上没有差异。接受乙碘油的组中，HSG后下腹部疼痛和阴道出血的发生率明显低于其他三组。乙碘油引起的盆腔感染或炎症的发生率明显低于水溶性造影剂。所有造影剂在输卵管、腹膜造影剂外溢和腹腔内分布方面均提供了可接受的诊断图像质量。水溶性造影剂对子宫腔和壶腹皱襞的显影明显优于乙碘油，乙碘油与高受孕率相关，作者认为其更适合用于HSG。
