Rasmussen F, Lindequist S, Larsen C, Justesen P
Department of Diagnostic Radiology, Odense University Hospital, Denmark.
Radiology. 1991 Apr;179(1):75-8. doi: 10.1148/radiology.179.1.1848716.
In a prospective randomized study, the number of pregnancies after hysterosalpingography (HSG) was estimated in 398 patients who had been infertile for longer than 1 year. Iohexol was used in 101 patients, ioxaglate in 102 patients, diatrizoate meglumine in 97 patients, and ethiodized poppy-seed oil in 98 patients. Ten months after HSG, the patient, referring physician, and/or hospital department was consulted for information about pregnancies. Questionnaires were obtained from the patients who became pregnant during the waiting period of 3 months. No differences in demographic parameters, infertility status, or diagnosis made with HSG were detected among the four contrast media groups. Significantly more patients became pregnant after HSG in the ethiodized poppy-seed oil group than in the three water-soluble contrast media groups (P less than .01). When only intrauterine pregnancies resulting in full-term births were considered, significant differences in pregnancy rates between the oil-soluble and the water-soluble contrast media groups became more obvious. In the group that received ethiodized poppy-seed oil, almost one-third of the infertile women had normal pregnancies and childbirths after HSG.
在一项前瞻性随机研究中，对398名不孕时间超过1年的患者进行了子宫输卵管造影术（HSG）后妊娠情况的评估。101名患者使用了碘海醇，102名患者使用了碘克沙醇，97名患者使用了泛影葡胺，98名患者使用了碘化罂粟籽油。HSG后10个月，向患者、转诊医生和/或医院科室咨询妊娠信息。对在3个月等待期内怀孕的患者进行问卷调查。在四种造影剂组中，未检测到人口统计学参数、不孕状况或HSG诊断方面的差异。碘化罂粟籽油组HSG后怀孕的患者明显多于三种水溶性造影剂组（P<0.01）。仅考虑足月分娩的宫内妊娠时，油溶性和水溶性造影剂组之间的妊娠率差异更为明显。在接受碘化罂粟籽油的组中，几乎三分之一的不孕女性在HSG后成功妊娠并分娩。
