使用LBC细胞培养的涎泪腺炎（SDA）病毒检测血清抗体。

Detection of serum antibodies using LBC cell-grown sialodacryoadenitis (SDA) virus.

作者信息

Utsumi K, Ishikawa T, Yokota Y, Yoshida K, Maeda K, Ohnishi K, Yanabe M, Fujiwara K

机构信息

Research Laboratories, Dainippon Pharmaceutical Co., Ltd., Osaka, Japan.

出版信息

Jikken Dobutsu. 1991 Jan;40(1):27-32. doi: 10.1538/expanim1978.40.1_27.

DOI:10.1538/expanim1978.40.1_27

PMID:1848824

Abstract

The TG strain of sialodacryoadenitis (SDA) virus propagated in LBC cell culture (TGr/LBC) reacted strongly with anti-TGr rat serum in complement fixation (CF) tests, showing much higher titers with anti-TGr rat serum than mouse hepatitis virus MHV-NuU antigen. The antigenicity was not affected after ether treatment while infectivity was lost. The TGr/LBC antigen might be useful in seromonitoring for SDA infection in rats.

摘要

在LBC细胞培养物中繁殖的涎泪腺炎（SDA）病毒TG株（TGr/LBC）在补体结合（CF）试验中与抗TGr大鼠血清发生强烈反应，与抗TGr大鼠血清的滴度比小鼠肝炎病毒MHV-NuU抗原高得多。经乙醚处理后，抗原性未受影响，但感染性丧失。TGr/LBC抗原可能有助于大鼠SDA感染的血清学监测。