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腹腔镜胆囊切除术的脊髓麻醉与全身麻醉:一项对照随机试验的中期分析

Spinal vs general anesthesia for laparoscopic cholecystectomy: interim analysis of a controlled randomized trial.

作者信息

Tzovaras George, Fafoulakis Frank, Pratsas Kostantinos, Georgopoulou Stavroula, Stamatiou Georgia, Hatzitheofilou Constantine

机构信息

Department of Surgery, University of Thessaly Medical School, University Hospital of Larissa, Larissa, Greece.

出版信息

Arch Surg. 2008 May;143(5):497-501. doi: 10.1001/archsurg.143.5.497.

Abstract

OBJECTIVE

To compare spinal anesthesia with the gold standard general anesthesia for elective laparoscopic cholecystectomy in healthy patients.

DESIGN

Controlled randomized trial.

SETTING

University hospital.

PATIENTS

One hundred patients with symptomatic gallstone disease and American Society of Anesthesiologists status I or II were randomized to have laparoscopic cholecystectomy under spinal (n = 50) or general (n = 50) anesthesia.

METHODS

Intraoperative parameters, postoperative pain, complications, recovery, and patient satisfaction at follow-up were compared between the 2 groups.

RESULTS

All the procedures were completed by the allocated method of anesthesia, as there were no conversions from spinal to general anesthesia. Pain was significantly less at 4 hours (P < .001), 8 hours (P < .001), 12 hours (P < .001), and 24 hours (P = .02) after the procedure for the spinal anesthesia group compared with those who received general anesthesia. There was no difference between the 2 groups regarding complications, hospital stay, recovery, or degree of satisfaction at follow-up.

CONCLUSIONS

Spinal anesthesia is adequate and safe for laparoscopic cholecystectomy in otherwise healthy patients and offers better postoperative pain control than general anesthesia without limiting recovery.

摘要

目的

比较脊髓麻醉与金标准全身麻醉用于健康患者择期腹腔镜胆囊切除术的效果。

设计

对照随机试验。

地点

大学医院。

患者

100例有症状胆结石疾病且美国麻醉医师协会分级为I或II级的患者被随机分为两组,分别接受脊髓麻醉(n = 50)或全身麻醉(n = 50)下的腹腔镜胆囊切除术。

方法

比较两组患者的术中参数、术后疼痛、并发症、恢复情况及随访时的患者满意度。

结果

所有手术均按分配的麻醉方法完成,无脊髓麻醉转为全身麻醉的情况。与接受全身麻醉的患者相比,脊髓麻醉组术后4小时(P <.001)、8小时(P <.001)、12小时(P <.001)和24小时(P =.02)时的疼痛明显减轻。两组在并发症、住院时间、恢复情况或随访时的满意度方面无差异。

结论

脊髓麻醉对于健康患者的腹腔镜胆囊切除术是充分且安全的,并且在不影响恢复的情况下,比全身麻醉能更好地控制术后疼痛。

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