Welander Maria, Abrahamsson Ingemar, Berglundh Tord
Department of Periodontology, The Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.
Clin Oral Implants Res. 2008 Jul;19(7):635-41. doi: 10.1111/j.1600-0501.2008.01543.x. Epub 2008 May 19.
The aim of the present study was to analyze the soft tissue barrier formed to implant abutments made of different materials.
Six Labrador dogs, about 1 year old, were used. All mandibular premolars and the first, second and third maxillary premolars were extracted. Three months later four implants (OsseoSpeed, 4.5 x 9 mm, Astra Tech Dental, Mölndal, Sweden) were placed in the edentulous premolar region on one side of the mandible and healing abutments were connected. One month later, the healing abutments were disconnected and four new abutments were placed in a randomized order. Two of the abutments were made of titanium (Ti), while the remaining abutments were made of ZrO(2) or AuPt-alloy. A 5-months plaque control program was initiated. Three months after implant surgery, the implant installation procedure and the subsequent abutment shift were repeated in the contra-lateral mandibular region. Two months later, the dogs were euthanized and biopsies containing the implant and the surrounding soft and hard peri-implant tissues were collected and prepared for histological analysis.
It was demonstrated that the soft tissue dimensions at Ti- and ZrO(2) abutments remained stable between 2 and 5 months of healing. At Au/Pt-alloy abutment sites, however, an apical shift of the barrier epithelium and the marginal bone occurred between 2 and 5 months of healing. In addition, the 80-mum-wide connective tissue zone lateral to the Au/Pt-alloy abutments contained lower amounts of collagen and fibroblasts and larger fractions of leukocytes than the corresponding connective tissue zone of abutments made of Ti and ZrO(2).
It is suggested that the soft tissue healing to abutments made of titanium and ZrO(2) is different to that at abutments made of AuPt-alloy.
本研究旨在分析由不同材料制成的种植体基台所形成的软组织屏障。
选用6只约1岁的拉布拉多犬。拔除所有下颌前磨牙以及上颌第一、第二和第三前磨牙。3个月后,在下颌一侧无牙的前磨牙区域植入4颗种植体(OsseoSpeed,4.5×9 mm,阿斯泰克牙科公司,瑞典默恩达尔),并连接愈合基台。1个月后,断开愈合基台,随机顺序植入4个新的基台。其中2个基台由钛(Ti)制成,其余基台由ZrO₂或金铂合金制成。启动为期5个月的菌斑控制计划。种植手术后3个月,在对侧下颌区域重复种植体植入过程及随后的基台更换。2个月后,对犬实施安乐死,收集包含种植体及周围软硬种植体周组织的活检样本,准备进行组织学分析。
结果表明,钛基台和ZrO₂基台处的软组织尺寸在愈合2至5个月期间保持稳定。然而,在金铂合金基台部位,愈合2至5个月期间屏障上皮和边缘骨出现根尖向移位。此外,金铂合金基台外侧80μm宽的结缔组织区域比钛基台和ZrO₂基台相应的结缔组织区域含有更少的胶原蛋白和成纤维细胞,以及更大比例的白细胞。
提示钛和ZrO₂基台的软组织愈合情况与金铂合金基台不同。