Bercin Sami, Kutluhan Ahmet, Yurttas Veysel, Yalciner Gokhan, Bozdemir Kazim, Sari Neslihan
Ankara Ataturk Education and Research Hospital ENT Clinic, Gurler sk. 129/3 Yenimahalle, Ankara, Turkey.
Eur Arch Otorhinolaryngol. 2008 Dec;265(12):1539-43. doi: 10.1007/s00405-008-0710-0. Epub 2008 May 21.
We investigated the prevalence of laryngopharyngeal reflux in patients with signs and symptoms of reflux, chronic otitis media and benign and malignant vocal cord lesions. Three groups of patients in Ankara Ataturk Education and Research Hospital ENT-Head and Neck Surgery Clinics were compared between 2005 and 2006. The first group had patients with signs and symptoms of reflux, the second group consisted of patients with chronic otitis media, and in the third group had patients with laryngeal pathology, i.e. vocal cord lesions. The results of pH monitoring of all the three groups of patients were analyzed for laryngopharyngeal reflux. In the evaluation, two different criteria, based on reflux number and time spent in reflux, were used. It was investigated whether there was a difference in terms of reflux among these three groups. Also, the effects of reflux in etiopathogenesis of chronic otitis media and vocal cord lesions are discussed. A total of 84 patients were studied, with 22 patients with signs and symptoms of reflux in Group 1, 42 patients with chronic otitis media in Group 2, and 20 patients with vocal cord lesions in Group 3. No statistical difference could be detected among the groups in terms of the two criteria mentioned above. The frequency of laryngopharyngeal reflux in patients with chronic otitis media and vocal cord lesions was found to be as high as than in the patients with signs and symptoms of reflux. During the treatment of chronic otitis media and laryngeal disorders, we advise reflux work-up, and in case if there is reflux, we recommend reflux treatment in addition to treatment of primary disease.
我们调查了有反流体征和症状、慢性中耳炎以及声带良恶性病变患者的喉咽反流患病率。2005年至2006年期间,对安卡拉阿塔图尔克教育与研究医院耳鼻喉头颈外科诊所的三组患者进行了比较。第一组为有反流体征和症状的患者,第二组由慢性中耳炎患者组成,第三组为有喉部病变(即声带病变)的患者。对所有三组患者的pH监测结果进行分析以评估喉咽反流情况。在评估中,采用了基于反流次数和反流持续时间的两种不同标准。研究了这三组患者在反流方面是否存在差异。此外,还讨论了反流在慢性中耳炎和声带病变病因学中的作用。总共研究了84例患者,第一组有22例有反流体征和症状的患者,第二组有42例慢性中耳炎患者,第三组有20例声带病变患者。根据上述两种标准,各组之间未检测到统计学差异。发现慢性中耳炎和声带病变患者的喉咽反流频率与有反流体征和症状的患者一样高。在慢性中耳炎和喉部疾病的治疗过程中,我们建议进行反流检查,如果存在反流,除了治疗原发疾病外,还建议进行反流治疗。