Rothman J E
Department of Molecular Biology, Princeton University, New Jersey.
Klin Wochenschr. 1991 Feb 6;69(3):98-104. doi: 10.1007/BF01795952.
A combination of cell-free biochemical and morphological studies has revealed that a coated bud-coated vesicle transport system shuttles newly synthesized proteins through the successive processing compartments of the Golgi apparatus. These "Golgi coated vesicles" operate in a manner formally analogous to the clathrin coated pit-coated vesicle system responsible for receptor-mediated endocytosis; however Golgi coated vesicles do not contain clathrin.
无细胞生物化学研究与形态学研究相结合,揭示出一种有被小芽 - 有被囊泡转运系统,该系统能将新合成的蛋白质穿梭运输至高尔基体的各个连续加工区室。这些“高尔基体有被囊泡”的运作方式在形式上类似于负责受体介导的内吞作用的网格蛋白包被小窝 - 包被囊泡系统;然而,高尔基体有被囊泡并不含有网格蛋白。