Suto Chikako, Hori Sadao, Kato Satoshi
Department of Ophthalmology, Tokyo Women's Medical University, Tokyo, Japan.
J Cataract Refract Surg. 2008 Jun;34(6):1001-6. doi: 10.1016/j.jcrs.2008.02.019.
To evaluate the outcomes in patients with diabetic retinopathy and cataract who had panretinal photocoagulation (PRP) first and cataract surgery second in 1 eye and cataract surgery followed by PRP in the fellow eye.
Department of Ophthalmology, Saiseikai Kurihashi Hospital, Saitama, Japan.
Fifty-eight eyes of 29 patients with similar bilateral cataracts and severe nonproliferative or early proliferative diabetic retinopathy were randomly assigned for treatment with cataract surgery performed after PRP (PRP-first group) or before PRP (surgery-first group). Treatment was performed in the opposite order in the contralateral eye. The main outcome measure was best corrected visual acuity (BCVA) 12 months after surgery. The secondary outcome measures were the laser parameters, progression of retinopathy and macular edema, and aqueous flare intensity.
The percentage of eyes with a BCVA of 20/40 or better was statistically significantly higher in the surgery-first group (96.6%) than in the PRP-first group (69.0%) (P = .012). The rate of the progression of macular edema was significantly decreased in the surgery-first group (P = .033). There was no significant difference between the 2 groups in the other outcome measures.
Although the order in which PRP and cataract surgery were performed had no effect on postoperative retinopathy, the BCVA was better and the rate of the progression of macular edema was decreased in the surgery-first group.
评估糖尿病视网膜病变合并白内障患者一眼先行全视网膜光凝(PRP)再行白内障手术,另一眼先行白内障手术再行PRP的治疗效果。
日本埼玉县西新井医院眼科。
29例患有相似双侧白内障及重度非增殖性或早期增殖性糖尿病视网膜病变的患者的58只眼被随机分配接受PRP后行白内障手术(PRP先行组)或PRP前行白内障手术(手术先行组)治疗。对侧眼以相反顺序进行治疗。主要观察指标为术后12个月的最佳矫正视力(BCVA)。次要观察指标为激光参数、视网膜病变和黄斑水肿的进展情况以及房水闪光强度。
手术先行组BCVA为20/40或更好的眼的百分比(96.6%)在统计学上显著高于PRP先行组(69.0%)(P = 0.012)。手术先行组黄斑水肿进展率显著降低(P = 0.033)。两组在其他观察指标上无显著差异。
虽然PRP和白内障手术的先后顺序对术后视网膜病变无影响,但手术先行组的BCVA更好,黄斑水肿进展率降低。