使用复方利多卡因乳膏进行局部麻醉并不能减轻输精管结扎术中的疼痛。

Topical anesthesia with EMLA does not decrease pain during vasectomy.

作者信息

Thomas Anil A, Nguyen Carvell T, Dhar Nivedita B, Sabanegh Edmund S, Jones J Stephen

机构信息

Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

出版信息

J Urol. 2008 Jul;180(1):271-3. doi: 10.1016/j.juro.2008.03.061. Epub 2008 May 21.

DOI:10.1016/j.juro.2008.03.061

PMID:18499175

Abstract

PURPOSE

Previous studies show conflicting results of the ability of EMLA (eutectic mixture of local anesthetics) to decrease pain during vasectomy. We examined the effectiveness of EMLA cream to decrease pain in patients undergoing bilateral percutaneous no-scalpel vasectomy.

MATERIALS AND METHODS

A prospective study was performed in which 316 patients used EMLA cream (178) or no topical anesthesia (138) before vasectomy. EMLA cream was applied by patients 1 hour before the scheduled time of surgery. Bilateral percutaneous no-scalpel vasectomy was then performed in the 2 groups with local infiltration of 1% lidocaine into the scrotal wall and vasal sheath. Following the procedure patients were asked to rate their associated pain using a visual analog scale. Statistical analysis was performed using the 2-sided Student t test.

RESULTS

Mean patient age was similar in the groups with and without EMLA (39.1 and 39.0 years, respectively). No significant difference in mean visual analog pain scores were noted between the EMLA and control groups (21.5 vs 21.0, p = 0.8).

CONCLUSIONS

Topical anesthesia with EMLA did not significantly decrease the pain associated with percutaneous vasectomy.

摘要

目的

先前的研究显示，关于复方利多卡因乳膏（局部麻醉剂的共熔混合物）在输精管结扎术中减轻疼痛的能力，结果相互矛盾。我们研究了复方利多卡因乳膏对接受双侧经皮无刀输精管结扎术患者减轻疼痛的有效性。

材料与方法

进行了一项前瞻性研究，其中316例患者在输精管结扎术前使用复方利多卡因乳膏（178例）或未进行局部麻醉（138例）。患者在预定手术时间前1小时涂抹复方利多卡因乳膏。然后对两组患者进行双侧经皮无刀输精管结扎术，并在阴囊壁和输精管鞘膜局部浸润1%利多卡因。术后要求患者使用视觉模拟量表对相关疼痛进行评分。采用双侧Student t检验进行统计分析。