Pujary P, Pujary K, Mahesh S G, Valiathan M
Department of ENT and Head and Neck Surgery, Kasturba Medical College, Manipal, Karnataka, India.
J Laryngol Otol. 2008 Jul;122(7):e15. doi: 10.1017/S0022215108002831. Epub 2008 May 23.
To report a rare genus of a fungal family commonly affecting the sinonasal region, which presented as a fungal granuloma of the inferior turbinate in an immunocompetent host. Such a case has not previously been reported.
A 49-year-old man presented with nasal conidiobolus limited to the left inferior turbinate, despite pre-operative fungal culture and tissue biopsy being negative for any fungal growth. On computed tomography scanning of the paranasal sinuses, and peri-operatively, the left inferior turbinate was seen to be enlarged and a bony, cartilaginous spur was found to impinge deep into the inferior turbinate. The spur may have caused microtrauma suitable for spore implantation, leading to fungal granuloma development. This unusual presentation highlights the fact that excision biopsy is diagnostic and therapeutic in such cases.
Conidiobolus coronata of the inferior turbinate is rare. Such a fungal granuloma may be large enough to be confused with a benign or malignant lesion of the nasal cavity.
报告一种常见于鼻窦区域的真菌科的罕见属,其在免疫功能正常的宿主中表现为下鼻甲真菌性肉芽肿。此前尚未有此类病例的报道。
一名49岁男性,尽管术前真菌培养和组织活检均未发现任何真菌生长,但鼻腔分生孢子菌仅局限于左下鼻甲。在鼻窦计算机断层扫描及手术过程中,可见左下鼻甲肿大,发现有一个骨软骨嵴深深刺入下鼻甲。该嵴可能造成了适合孢子植入的微创伤,导致真菌性肉芽肿形成。这种不寻常的表现凸显了在这类病例中切除活检具有诊断和治疗作用这一事实。
下鼻甲冠状分生孢子菌罕见。这种真菌性肉芽肿可能大到足以与鼻腔的良性或恶性病变相混淆。