Sharath Savitha, Bansal Abhinav, Sinha Surabhi, Ahuja Arvind
Department of Dermatology, Venereology and Leprosy, Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India.
Department of Dermatology, Venereology and Leprosy, Lady Harding Medical College, New Delhi, India.
Am J Trop Med Hyg. 2024 Oct 29;112(1):158-160. doi: 10.4269/ajtmh.24-0196. Print 2025 Jan 8.
There are no standard guidelines on the management of Conidiobolus infections, and many antifungals have been used, either alone or in combination. Relapses are common even after successful management. Although localized, they can result in severe facial disfigurement and may rarely cause disseminated entomophthoromycosis, which can have fatal complications. We present a case of biopsy-proven conidiobolomycosis in a young immunocompetent male patient with progressive unilateral rhinofacial swelling who was successfully treated with itraconazole monotherapy and showed no relapse after 1 year of therapy.
目前尚无关于冠状耳霉感染管理的标准指南，许多抗真菌药物已被单独或联合使用。即使在成功治疗后，复发也很常见。虽然感染局限，但可导致严重的面部畸形，并且很少会引起播散性虫霉病，后者可能会出现致命并发症。我们报告一例经活检证实的冠状耳霉病病例，患者为一名年轻的免疫功能正常男性，有进行性单侧鼻面部肿胀，接受伊曲康唑单药治疗成功，治疗1年后未复发。
