Varshney Saurabh, Gupta Pratima, Bist Sampan Singh, Bhagat Sanjeev
Department of ENT, All India Institute of Medical Sciences, Rishikesh - 249201, India.
Ear Nose Throat J. 2015 Apr-May;94(4-5):E32-5.
Fungal infections are common in tropical countries such as India. Very few clinical cases caused by the Entomophthorales Zygomycetes have been reported. Rhinofacial infection is a rare form of zygomycosis in humans, and only limited information regarding optimal treatment is available. We report here a rare case of rhinofacial Conidiobolus coronatus infection in a previously healthy 18-year-old man who presented with a fungal granuloma of the right inferior turbinate and face. Diagnosis was confirmed by microbiologic culture from a tissue biopsy. The infection was successfully treated with surgery and itraconazole therapy for 12 months. The clinical presentation and treatment of this rare, chronic, indolent form of fungal infection are highlighted in this article.
真菌感染在印度等热带国家很常见。由虫霉目接合菌引起的临床病例报道极少。鼻面部感染是人类接合菌病的一种罕见形式,关于最佳治疗的信息有限。我们在此报告一例罕见的鼻面部冠状耳霉感染病例,患者为一名18岁既往健康男性,表现为右下鼻甲和面部真菌性肉芽肿。通过组织活检的微生物培养确诊。该感染通过手术及伊曲康唑治疗12个月后成功治愈。本文重点介绍了这种罕见、慢性、惰性真菌感染的临床表现及治疗。