Hutchison James S, Doherty Dermot R, Orlowski James P, Kissoon Niranjan
Department of Critical Care Medicine, University of Toronto and Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
Pediatr Clin North Am. 2008 Jun;55(3):529-44, ix. doi: 10.1016/j.pcl.2008.02.011.
Cardiac arrest is associated with high morbidity and mortality in children. Hypothermia therapy has theoretical benefits on brain preservation and has the potential to decrease morbidity and mortality in children following cardiac arrest. The American Heart Association guidelines recommend that it should be considered in children after cardiac arrest. Methods of inducing hypothermia include simple surface cooling techniques, intravenous boluses of cold saline, gastric lavage with ice-cold normal saline, and using the temperature control device with extracorporeal life support. We recommend further study before a strong recommendation can be made to use hypothermia therapy in children with cardiac arrest.
心脏骤停在儿童中与高发病率和死亡率相关。低温治疗对脑保护具有理论上的益处，并且有可能降低儿童心脏骤停后的发病率和死亡率。美国心脏协会指南建议在儿童心脏骤停后应考虑采用该疗法。诱导低温的方法包括简单的体表降温技术、静脉推注冷盐水、用冰冷的生理盐水洗胃以及使用带有体外生命支持的温度控制装置。在能够强烈推荐对心脏骤停儿童使用低温治疗之前，我们建议进行进一步研究。
