Department of Urology, Klinikum Grosshadern, Ludwig-Maximilian-University Munich, Germany.
Urology. 2011 Sep;78(3):708-12. doi: 10.1016/j.urology.2011.03.068. Epub 2011 Jul 20.
To evaluate prospectively detailed urodynamic parameters before and after retrourethral transobturator sling (RTS) placement and the impact of adverse preoperative urodynamic parameters on postoperative outcome.
Fifty-five consecutive patients with postprostatectomy stress urinary incontinence (SUI) underwent urodynamics with pressure flow and abdominal leak point pressure (ALPP) measurements, quality of life, 1-hour pad test, and daily pad use assessment before RTS (AdVance) and 12 months postoperatively. Volume of first sensation and first desire to void, maximum cystometric capacity (MCC), ALPP, maximum flow rate (Qmax.), average flow rate, time to Qmax., detrusor voiding pressure at Qmax., voiding time, and postvoid residual urine volume (PVR) were assessed. The success rate was defined as cure (no or one dry "security" pad) or improvement (1-2 pads or pad reduction≥50%). Adverse parameters included ALPP≤30 cm H2O, Qmax.≤10 mdL/s, and MCC≤200 mL.
Success rate after RTS was 73% (40/55 patients). Mean follow-up was 21±11.7 (range, 12-41) months. Only ALPP changed significantly (61±14.2 vs 79±20.4 cm H2O). No PVR>30 mL, de novo reduced bladder compliance and hypo- or overactivity were observed. Urine loss by 1-hour pad test (136.1±119.4 vs 39.4±77.0) and daily pad use (4.6±2.0 vs 1.9±2.1) decreased significantly. Adverse preoperative urodynamic parameters were not associated with postoperative outcome.
The RTS is an effective and safe device for SUI treatment without signs of compression or obstruction of the urethra or any influence on voiding parameters. Adverse preoperative urodynamic parameters have no influence on postoperative outcome.
前瞻性评估经尿道后尿道悬吊带(RTS)置入前后详细的尿动力学参数,并评估术前不良尿动力学参数对术后结果的影响。
55 例前列腺切除术后压力性尿失禁(SUI)患者接受压力-流率和腹压漏点压力(ALPP)测量、生活质量评估、1 小时尿垫试验和日常尿垫使用评估,分别在 RTS(Advance)前和术后 12 个月进行。评估首次感觉和首次排尿意愿的尿量、最大膀胱容量(MCC)、ALPP、最大尿流率(Qmax.)、平均尿流率、达到 Qmax.的时间、最大逼尿肌排空压力、排尿时间和残余尿量(PVR)。成功率定义为治愈(无或仅使用 1 个干燥“安全”尿垫)或改善(使用 1-2 个尿垫或尿垫减少≥50%)。不良参数包括 ALPP≤30cmH2O、Qmax.≤10mdL/s 和 MCC≤200mL。
RTS 后成功率为 73%(40/55 例患者)。平均随访时间为 21±11.7(范围 12-41)个月。仅 ALPP 显著改变(61±14.2 比 79±20.4cmH2O)。未观察到 PVR>30mL、新出现的膀胱顺应性降低、低顺应性或高顺应性活动。1 小时尿垫试验尿失禁量(136.1±119.4 比 39.4±77.0)和每日尿垫使用量(4.6±2.0 比 1.9±2.1)显著减少。术前不良尿动力学参数与术后结果无关。
RTS 是一种有效且安全的治疗 SUI 的方法,不会导致尿道受压或梗阻,也不会对排尿参数产生任何影响。术前不良尿动力学参数对术后结果无影响。