Flu Hans, van der Hage Jos H, Knippenberg Bob, Merkus Jos W, Hamming Jaap F, Lardenoye Jan Willem H
Department of Vascular Surgery at Haga Hospital location Leyweg, The Hague, The Netherlands.
J Vasc Surg. 2008 Aug;48(2):368-376. doi: 10.1016/j.jvs.2008.03.029. Epub 2008 May 23.
This study determined the average estimated total costs after treatment for peripheral arterial occlusive disease (PAOD) and evaluated the effect of postoperative complications and their consequences for the total costs.
Cost data on all admissions involving treatment for PAOD from January 2007 until July 2007 were collected. A prospective analysis was made using the patient-related risk factor and comorbidity (Society for Vascular Surgery/International Society of Cardiovascular Surgeons) classification, primary and secondary treatment, and prospectively registered complications. At admission, patients without complications were placed in group A, and those with complications were in group B. Prospectively registered complications were divided into patient management (I), surgical technique (II), patient's disease (III), and outside surgical department (IV). The consequences of these were divided into minor complication, no long-term consequence (1A), additional medication or transfusion (1B), surgical reoperation (2A), prolonged hospital stay (2B), irreversible physical damage (3), and death (4). The main outcome measures were total costs of patients and costs per patient (PP), with or without the presence of complications, cost of complications and costs per complication (PC), and the costs of their consequences calculated in euros (euro).
Ninety patients (mean age, 71.4 years; 59% men) were included. Group B patients had a significantly higher American Society of Anesthesiologists (4) and Fontaine (3) classification and more secondary procedures. Total costs were euro 1,716,852: group A, euro 512,811 (PP euro 12,820); and group B, euro 1,204,042 (PP euro 24,081). The costs of the 115 complications were euro 568,500 (PC euro 4943). Split by the cause of the complication, costs were I, euro 95,924 (PC euro 2998); II, euro 163,137 (PC euro 8157); III, euro 289,578 (PC euro 5171); and IV, euro 19,861 (PC euro 2837). The increase of costs in group B was mainly caused by additional medication or transfusion (1B) euro 348,293 (61.3%), a surgical reoperation (2A) euro 118,054 (20.8%), or prolonged hospital stay (2B) euro 60,451 (10.6%). Patients who died caused 23% of the total costs.
Complications cause an increase of the average estimated total costs in the treatment for peripheral arterial occlusive disease and are responsible for 33% of these total costs. The most expensive complications were errors in surgical technique and patient's disease, resulting in surgical reoperation or additional medication, or both, or transfusion, the two most expensive consequences.
本研究确定了外周动脉闭塞性疾病(PAOD)治疗后的平均估计总成本,并评估了术后并发症及其后果对总成本的影响。
收集了2007年1月至2007年7月所有涉及PAOD治疗的住院费用数据。采用与患者相关的危险因素和合并症(血管外科学会/国际心血管外科医师学会)分类、一级和二级治疗以及前瞻性登记的并发症进行前瞻性分析。入院时,无并发症的患者归入A组,有并发症的患者归入B组。前瞻性登记的并发症分为患者管理(I)、手术技术(II)、患者疾病(III)和外科科室以外(IV)。其后果分为轻度并发症,无长期后果(1A)、额外用药或输血(1B)、再次手术(2A)、住院时间延长(2B)、不可逆身体损伤(3)和死亡(4)。主要结局指标为患者的总成本和每位患者的成本(PP),有或无并发症、并发症成本和每例并发症成本(PC),以及其后果成本以欧元(€)计算。
纳入90例患者(平均年龄71.4岁;59%为男性)。B组患者美国麻醉医师协会(4)和Fontaine(3)分级显著更高,且二级手术更多。总成本为1,716,852欧元:A组为512,811欧元(PP为12,820欧元);B组为1,204,042欧元(PP为24,081欧元)。115例并发症的成本为568,500欧元(PC为4943欧元)。按并发症原因分类,成本分别为:I,95,924欧元(PC为2998欧元);II,163,137欧元(PC为8157欧元);III,289,578欧元(PC为5171欧元);IV,19,861欧元(PC为2837欧元)。B组成本增加主要由额外用药或输血(1B)348,293欧元(61.3%)、再次手术(2A)118,054欧元(20.8%)或住院时间延长(2B)60,451欧元(10.6%)所致。死亡患者造成了23%的总成本。
并发症导致外周动脉闭塞性疾病治疗的平均估计总成本增加,占这些总成本的33%。最昂贵的并发症是手术技术和患者疾病方面的错误,导致再次手术或额外用药,或两者兼有,或输血,这是两个最昂贵的后果。