Tay Shirli, Abdulnabi Sami, Saffaf Omar, Harroun Nikolai, Yang Chao, Semenkovich Clay F, Zayed Mohamed A
Department of Surgery, Section of Vascular Surgery, Washington University School of Medicine, St. Louis, MO.
Department of Internal Medicine, Division of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St. Louis, MO.
Clin Diabetes. 2021 Oct;39(4):358-388. doi: 10.2337/cd21-0019.
Chronic limb-threatening ischemia (CLTI) is the most severe form of peripheral artery disease. It is estimated that 60% of all nontraumatic lower-extremity amputations performed annually in the United States are in patients with diabetes and CLTI. The consequences of this condition are extraordinary, with substantial patient morbidity and mortality and high socioeconomic costs. Strategies that optimize the success of arterial revascularization in this unique patient population can have a substantial public health impact and improve patient outcomes. This article provides an up-to-date comprehensive assessment of management strategies for patients afflicted by both diabetes and CLTI.
慢性肢体威胁性缺血（CLTI）是外周动脉疾病最严重的形式。据估计，美国每年进行的所有非创伤性下肢截肢手术中，60%是针对患有糖尿病和CLTI的患者。这种疾病的后果非常严重，患者发病率和死亡率高，社会经济成本也很高。优化这一特殊患者群体动脉血运重建成功率的策略可产生重大的公共卫生影响并改善患者预后。本文对同时患有糖尿病和CLTI的患者的管理策略进行了最新的全面评估。
